SCHEMBL3404753

SCHEMBL3404753

C1=C[Si]1(c1ccccc1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.35
DPP4 P27487 2/20 0.33
F2 P00734 1/20 0.33
TSHR P16473 4/20 0.32
CA1 P00915 3/20 0.32
CA2 P00918 3/20 0.32
CA9 Q16790 3/20 0.32
TDP1 Q9NUW8 3/20 0.32
CA12 O43570 2/20 0.32
CA3 P07451 2/20 0.32
CA4 P22748 2/20 0.32
CA14 Q9ULX7 2/20 0.32
CA7 P43166 2/20 0.32
GLA P06280 1/20 0.32
LMNA P02545 1/20 0.32
ALOX12 P18054 1/20 0.32
ACHE P22303 1/20 0.32
CA6 P23280 1/20 0.30
CA5A P35218 1/20 0.30
PLA2G7 Q13093 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1073802 0.87 ALDH1A1 (0.32) ALDH1A1DPP4F2
SCHEMBL18069045 0.74 ACHE (0.43) TSHRCA1CA2CA9TDP1
SCHEMBL1426708 0.69 CALM1 (0.41) ALDH1A1TSHRCA1CA2CA9
SCHEMBL1249832 0.69 CALM1 (0.41) ALDH1A1TSHRCA1CA2CA9
SCHEMBL1425981 0.69 CALM1 (0.41) ALDH1A1TSHRCA1CA2CA9
SCHEMBL8897208 0.64 ALDH1A1 (0.39) ALDH1A1TSHRCA1CA2CA9
SCHEMBL17702069 0.62 ALDH1A1 (0.33) ALDH1A1TSHRCA1CA2CA9
SCHEMBL5554735 0.62 CALM1 (0.35) ALDH1A1TSHRCA1CA2CA9
SCHEMBL7715185 0.62 MAPT (0.35) ALDH1A1TSHRCA1CA2CA9
SCHEMBL859982 0.62 ALDH1A1 (0.33) ALDH1A1TSHRCA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2010080878-A PRINTED CIRCUIT BOARD AND METHOD OF MANUFACTURING THE SAME SONY CHEMICAL & INFORMATION DEVICE CORP 2010-04-08 JP disclosed
US-7005400-B2 Component of catalyst for polymerizing olefin, catalyst for polymerizing olefin and process for polymerizing olefin JAPAN POLYCHEM CORPORATION (JP) 2006-02-28 US disclosed
US-20030054952-A1 Component of catalyst for polymerizing olefin, catalyst for polymerizing olefin and process for polymerizing olefin JAPAN POLYCHEM CORPORATION (JP) 2003-03-20 US disclosed
EP-1247573-A1 Component of catalyst for polymerizing olefin, catalyst for polymerizing olefin and process for polymerizing olefin Japan Polychem Corporation, Catalyst Research & Development Center (JP) 2002-10-09 EP disclosed