SCHEMBL5554735

SCHEMBL5554735

c1ccc([Si]2(c3ccccc3)[Si](c3ccccc3)(c3ccccc3)[Si](c3ccccc3)(c3ccccc3)[Si]3([Si]2(c2ccccc2)c2ccccc2)[Si](c2ccccc2)(c2ccccc2)[Si](c2ccccc2)(c2ccccc2)[Si](c2ccccc2)(c2ccccc2)[Si]3(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.35
ALDH1A1 P00352 3/20 0.33
NPC1 O15118 1/20 0.32
MAPK1 P28482 1/20 0.32
RAB9A P51151 1/20 0.32
CYP2A6 P11509 1/20 0.32
MAOB P27338 1/20 0.30
TSHR P16473 3/20 0.30
CA1 P00915 2/20 0.30
CA2 P00918 2/20 0.30
CA9 Q16790 2/20 0.30
TDP1 Q9NUW8 2/20 0.30
CA12 O43570 1/20 0.30
GLA P06280 1/20 0.30
CA3 P07451 1/20 0.30
CA4 P22748 1/20 0.30
CA14 Q9ULX7 1/20 0.30
LMNA P02545 1/20 0.30
ALOX12 P18054 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1425981 0.89 CALM1 (0.41) CALM1ALDH1A1CYP2A6MAOBTSHR
SCHEMBL1426708 0.89 CALM1 (0.41) CALM1ALDH1A1CYP2A6MAOBTSHR
SCHEMBL1249832 0.89 CALM1 (0.41) CALM1ALDH1A1CYP2A6MAOBTSHR
SCHEMBL3642337 0.69 ALDH1A1 (0.40) CALM1ALDH1A1MAPK1LMNA
SCHEMBL14743135 0.64
SCHEMBL9177736 0.63 LMNA (0.33) ALDH1A1TSHRLMNAALOX12ACHE
SCHEMBL9181345 0.63 LMNA (0.33) ALDH1A1TSHRLMNAALOX12ACHE
SCHEMBL8897208 0.62 ALDH1A1 (0.39) CALM1ALDH1A1MAPK1TSHRCA1
SCHEMBL3404753 0.62 ALDH1A1 (0.35) ALDH1A1TSHRCA1CA2CA9
SCHEMBL859982 0.60 ALDH1A1 (0.33) ALDH1A1TSHRCA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1134224-B1 Cyclosilane compound, and solution composition and process for forming a silicon film JSR CORP (JP) 2007-05-30 EP disclosed
EP-1134224-A2 Cyclosilane compound, and solution composition and process for forming a silicon film JSR Corporation (JP) 2001-09-19 EP disclosed
US-20010021760-A1 Novel cyclosilane compound, and solution composition and process for forming a silicon film JSR CORPORATION (JP) 2001-09-13 US disclosed