Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | BCL9 | O00512 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3401402 | 0.83 | HTT (0.46) | GAASMN1; SMN2ALDH1A1MAPTHTT | |
| SCHEMBL3404977 | 0.76 | MGLL (0.51) | MGLLGAABCL9CTNNB1SMN1; SMN2 | |
| SCHEMBL29935467 | 0.74 | MGLL (0.60) | MGLLGAABCL9CTNNB1SMN1; SMN2 | |
| SCHEMBL278663 | 0.73 | BCL9 (0.62) | MGLLGAABCL9CTNNB1SMN1; SMN2 | |
| SCHEMBL27969685 | 0.73 | GAA (0.61) | MGLLGAABCL9CTNNB1SMN1; SMN2 | |
| SCHEMBL1733955 | 0.72 | MGLL (0.57) | MGLLGAABCL9CTNNB1SMN1; SMN2 | |
| 4-Nitrophenyl Ethylcarbamate SCHEMBL1695035 | 0.72 | MGLL (0.74) | MGLLGAABCL9CTNNB1SMN1; SMN2 | |
| SCHEMBL260968 | 0.72 | MGLL (0.68) | MGLLGAABCL9CTNNB1SMN1; SMN2 | |
| SCHEMBL3404975 | 0.71 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1MAPTKMT2AL3MBTL1 | |
| SCHEMBL21410733 | 0.71 | GAA (0.71) | MGLLGAABCL9CTNNB1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252604-A1 | THIAZOLE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R-Tech Ueno, Ltd. (JP) | 2010-11-24 | — | — | EP | disclosed |
| WO-2009096609-A1 | THIAZOLE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R-TECH UENO, LTD. (JP) | 2009-08-06 | — | — | WO | disclosed |