Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | BCL9 | O00512 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3407934 | 0.84 | MEN1 (0.41) | GAAALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL3401395 | 0.83 | MAPT (0.40) | GAAALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL18412616 | 0.77 | MGLL (0.53) | MGLLGAABCL9CTNNB1ALDH1A1 | |
| SCHEMBL7308415 | 0.77 | MGLL (0.53) | MGLLGAABCL9CTNNB1ALDH1A1 | |
| SCHEMBL14907653 | 0.77 | MGLL (0.72) | MGLLGAABCL9CTNNB1ALDH1A1 | |
| SCHEMBL3404972 | 0.76 | MGLL (0.51) | MGLLGAABCL9CTNNB1ALDH1A1 | |
| SCHEMBL14907652 | 0.76 | MGLL (0.67) | MGLLGAABCL9CTNNB1SMN1; SMN2 | |
| SCHEMBL11980594 | 0.76 | MGLL (0.60) | MGLLGAABCL9CTNNB1ALDH1A1 | |
| SCHEMBL18984707 | 0.76 | KMT2A (0.47) | GAAALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL10674760 | 0.74 | GAA (0.56) | MGLLGAABCL9CTNNB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252604-A1 | THIAZOLE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R-Tech Ueno, Ltd. (JP) | 2010-11-24 | — | — | EP | disclosed |
| WO-2009096609-A1 | THIAZOLE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R-TECH UENO, LTD. (JP) | 2009-08-06 | — | — | WO | disclosed |