Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.40 |
| ▸ | ELANE | P08246 | 6/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3401395 | 0.88 | MAPT (0.40) | MEN1KMT2ABCHECHRM2ELANE | |
| SCHEMBL3404977 | 0.84 | MGLL (0.51) | KMT2AMAPTGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL3406288 | 0.77 | NPC1 (0.58) | MEN1KMT2AMAPTKDM4EGAA | |
| SCHEMBL3404604 | 0.76 | L3MBTL1 (0.42) | MAPTKDM4EGLATDP1HTT | |
| SCHEMBL3401758 | 0.74 | AOC3 (0.54) | HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL3407932 | 0.73 | HTT (0.47) | MEN1KMT2ABCHECHRM2ELANE | |
| SCHEMBL10866251 | 0.70 | MAPT (0.46) | KMT2AELANEMIFMAPTKDM4E | |
| SCHEMBL4057059 | 0.69 | ELANE (0.70) | MEN1KMT2AELANEMIFMAPT | |
| SCHEMBL27774480 | 0.69 | MEN1 (0.53) | MEN1KMT2ABCHECHRM2ELANE | |
| SCHEMBL3894800 | 0.69 | TSHR (0.42) | CHRM2MIFMAPTKDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252604-A1 | THIAZOLE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R-Tech Ueno, Ltd. (JP) | 2010-11-24 | — | — | EP | disclosed |
| WO-2009096609-A1 | THIAZOLE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R-TECH UENO, LTD. (JP) | 2009-08-06 | — | — | WO | disclosed |