Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.48 |
| ▸ | KDM5A | P29375 | 2/20 | 0.43 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | ICMT | O60725 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1404085 | 1.00 | LMNA (0.68) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL1262955 | 1.00 | LMNA (0.68) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL1404155 | 1.00 | LMNA (0.68) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL9807808 | 1.00 | LMNA (0.68) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL1404090 | 1.00 | LMNA (0.68) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL23888725 | 1.00 | LMNA (0.68) | LMNAALDH1A1TSHRMEN1KMT2A | |
| Octanol SCHEMBL11125952 | 1.00 | LMNA (0.68) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL4937294 | 1.00 | LMNA (0.68) | LMNAALDH1A1TSHRMEN1KMT2A | |
| Octanol SCHEMBL22656886 | 1.00 | LMNA (0.68) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL8053580 | 1.00 | LMNA (0.68) | LMNAALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476424-B2 | Removal of acids from tertiary amide solvents | TATE & LYLE TECHNOLOGY LIMITED (GB) | 2013-07-02 | — | — | US | disclosed |
| EP-2254677-A1 | REMOVAL OF ACIDS FROM TERTIARY AMIDE SOLVENTS | Tate & Lyle Technology Limited (GB) | 2010-12-01 | — | — | EP | disclosed |
| US-20090259034-A1 | REMOVAL OF ACIDS FROM TERTIARY AMIDE SOLVENTS | TATE & LYLE TECHNOLOGY LIMITED (GB) | 2009-10-15 | — | — | US | disclosed |
| WO-2009117317-A1 | REMOVAL OF ACIDS FROM TERTIARY AMIDE SOLVENTS | TATE & LYLE TECHNOLOGY LTD (GB) | 2009-09-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090259034-A1 | REMOVAL OF ACIDS FROM TERTIARY AMIDE SOLVENTS | ACMSD, NAAA, ABHD6 | LMNA 3638/4885ALDH1A1 673/4885TSHR 2001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.