Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxirane SCHEMBL524300 | 0.89 | ALDH1A1 (0.39) | TSHRALDH1A1 | |
| Oxirane SCHEMBL1717397 | 0.89 | ALDH1A1 (0.39) | TSHRALDH1A1 | |
| Tetrahydrofuran SCHEMBL9062179 | 0.87 | ALDH1A1 (0.50) | TSHRALDH1A1 | |
| SCHEMBL360869 | 0.82 | TSHR (0.33) | TSHRALDH1A1 | |
| SCHEMBL29012014 | 0.81 | ALDH1A1 (0.44) | TSHRALDH1A1 | |
| Cyclohexane SCHEMBL7155261 | 0.81 | ALDH1A1 (0.44) | TSHRALDH1A1 | |
| Fluoride SCHEMBL9562346 | 0.80 | ALDH1A1 (0.50) | TSHRALDH1A1 | |
| SCHEMBL3406772 | 0.78 | TSHR (0.30) | TSHR | |
| SCHEMBL8613971 | 0.76 | ALDH1A1 (0.54) | TSHRALDH1A1 | |
| SCHEMBL157380 | 0.76 | ALDH1A1 (0.54) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2205203-B1 | NOVEL COMPOUNDS PREPARED BY ADDING AN OXETANE DERIVATIVE TO AN ALCOHOL | CECALC (FR) | 2013-01-23 | — | — | EP | claimed |
| US-8258189-B2 | Compounds prepared by adding an oxetane derivative to an alcohol | CECALC (FR) | 2012-09-04 | — | — | US | claimed |
| CN-101827577-A | Novel compounds prepared by adding an oxetane derivative to an alcohol | SEPPIC SA | 2010-09-08 | — | — | CN | claimed |
| US-20100216894-A1 | NOVEL COMPOUNDS PREPARED BY ADDING AN OXETANE DERIVATIVE TO AN ALCOHOL | CECALC (FR) | 2010-08-26 | — | — | US | claimed |
| EP-2205203-A1 | NOVEL COMPOUNDS PREPARED BY ADDING AN OXETANE DERIVATIVE TO AN ALCOHOL | Société d'Exploitation de Produits pour les Industries Chimiques SEPPIC (FR) | 2010-07-14 | — | — | EP | claimed |
| WO-2009050405-A1 | NOVEL COMPOUNDS PREPARED BY ADDING AN OXETANE DERIVATIVE TO AN ALCOHOL | SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) | 2009-04-23 | — | — | WO | claimed |
| US-8258189-B2 | Compounds prepared by adding an oxetane derivative to an alcohol | CECALC (FR) | 2012-09-04 | — | — | US | disclosed |
| CN-101827577-A | Novel compounds prepared by adding an oxetane derivative to an alcohol | SEPPIC SA | 2010-09-08 | — | — | CN | disclosed |
| US-20100216894-A1 | NOVEL COMPOUNDS PREPARED BY ADDING AN OXETANE DERIVATIVE TO AN ALCOHOL | CECALC (FR) | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216894-A1 | NOVEL COMPOUNDS PREPARED BY ADDING AN OXETANE DERIVATIVE TO AN ALCOHOL | ADH1A, ADH5, ADH1C | TSHR 4196/4885ALDH1A1 58/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.