Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3405230 | 0.87 | MYC (0.42) | ALDH1A1MAPTGAASMN1; SMN2KMT2A | |
| SCHEMBL3406875 | 0.85 | ALDH1A1 (0.41) | ALDH1A1HPGDTDP1L3MBTL1MAPK1 | |
| SCHEMBL3407747 | 0.81 | CNR2 (0.39) | EGFRALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL3408784 | 0.78 | LMNA (0.41) | ALDH1A1HPGDL3MBTL1MAPK1MAPT | |
| SCHEMBL3282414 | 0.74 | NOTUM (0.41) | ALDH1A1HPGDMAPTGAAKMT2A | |
| SCHEMBL3405019 | 0.73 | POLB (0.42) | EGFRALDH1A1TDP1L3MBTL1MAPT | |
| SCHEMBL3404051 | 0.72 | EGFR (0.48) | EGFRHPGDMAPTGAAKMT2A | |
| SCHEMBL155033 | 0.71 | SLC28A3 (0.34) | — | |
| SCHEMBL11213858 | 0.69 | — | — | |
| SCHEMBL2804217 | 0.69 | HTR2A (0.34) | ALDH1A1HPGDMAPTGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427431-B1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2013-05-01 | — | — | EP | disclosed |
| EP-2256103-A1 | Novel indicator platform | Biosynth AG (CH) | 2010-12-01 | — | — | EP | disclosed |