Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.61 |
| ▸ | DRD2 | P14416 | 10/20 | 0.60 |
| ▸ | DRD3 | P35462 | 8/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.57 |
| ▸ | DRD4 | P21917 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3407957 | 0.86 | SLC6A2 (0.67) | SLC6A2SLC6A4DRD2DRD3ADRA1A | |
| SCHEMBL13160190 | 0.85 | HTR1A (0.57) | SLC6A2SLC6A4DRD2DRD3ADRA1A | |
| SCHEMBL3402701 | 0.84 | DRD2 (0.68) | SLC6A2SLC6A4DRD2DRD3ADRA1A | |
| SCHEMBL183129 | 0.82 | SLC6A2 (0.57) | SLC6A2SLC6A4DRD2DRD3ADRA1A | |
| SCHEMBL1028007 | 0.78 | KDM4E (0.62) | SLC6A2SLC6A4DRD2ADRA1AALDH1A1 | |
| SCHEMBL11606079 | 0.78 | ALDH1A1 (0.66) | DRD2ALDH1A1LMNADRD4HTR1A | |
| Hydrochloric Acid SCHEMBL11460843 | 0.77 | ALDH1A1 (0.65) | DRD2ALDH1A1LMNADRD4HTR1A | |
| SCHEMBL2001110 | 0.76 | ALDH1A1 (0.66) | SLC6A2SLC6A4DRD2DRD3ADRA1A | |
| SCHEMBL12570054 | 0.76 | HTR1A (0.68) | SLC6A2SLC6A4DRD2DRD3ADRA1A | |
| SCHEMBL11609088 | 0.76 | ALDH1A1 (0.63) | DRD2ALDH1A1LMNADRD4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8575185-B2 | Compositions, synthesis, and methods of utilizing quinazolinedione derivatives | REVIVA PHARMACEUTICALS, INC. (US) | 2013-11-05 | — | — | US | disclosed |
| WO-2010099503-A1 | COMPOSITIONS, SYNTHESIS, AND METHODS OF UTILIZING QUINAZOLINEDIONE DERIVATIVES | REVIVA PHARMACEUTICALS, INC. (US) | 2010-09-02 | — | — | WO | disclosed |
| US-20100222359-A1 | COMPOSITIONS, SYNTHESIS, AND METHODS OF UTILIZING QUINAZOLINEDIONE DERIVATIVES | REVIVA PHARMACEUTICALS, INC. | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222359-A1 | COMPOSITIONS, SYNTHESIS, AND METHODS OF UTILIZING QUINAZOLINEDIONE DERIVATIVES | GRIN2D, GRIK5, GRIK4 | SLC6A2 643/4885SLC6A4 458/4885DRD2 82/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.