Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | F13A1 | P00488 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 5/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6937148 | 0.75 | MAOA (0.40) | KDM4EMAPTALDH1A1LMNAHPGD | |
| SCHEMBL16457166 | 0.74 | EPHX1 (0.46) | KDM4EMAPTLMNAKMT2AF13A1 | |
| SCHEMBL1661397 | 0.69 | KDM4E (0.54) | KDM4EMAPTALDH1A1LMNAHPGD | |
| SCHEMBL7068909 | 0.69 | ALDH1A1 (0.49) | MAPTALDH1A1LMNAHSD17B10KMT2A | |
| SCHEMBL30252290 | 0.68 | MAPT (0.66) | KDM4EMAPTALDH1A1LMNAHPGD | |
| SCHEMBL11754501 | 0.67 | ALDH1A1 (0.47) | KDM4EMAPTALDH1A1LMNAHPGD | |
| SCHEMBL4696811 | 0.67 | HSD17B10 (0.47) | MAPTALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL7841883 | 0.67 | ALDH1A1 (0.47) | KDM4EMAPTALDH1A1LMNAHSD17B10 | |
| SCHEMBL5782916 | 0.66 | ALDH1A1 (0.42) | ALDH1A1HSD17B10KMT2ASMN1; SMN2 | |
| SCHEMBL5782169 | 0.66 | DYRK1A (0.43) | MAPTALDH1A1LMNAHSD17B10CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252604-A1 | THIAZOLE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R-Tech Ueno, Ltd. (JP) | 2010-11-24 | — | — | EP | claimed |
| WO-2009096609-A1 | THIAZOLE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R-TECH UENO, LTD. (JP) | 2009-08-06 | — | — | WO | claimed |