Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701540 | 0.85 | IKBKB (0.40) | PLK1MAPTHPGDMEN1LMNA | |
| SCHEMBL7841883 | 0.77 | ALDH1A1 (0.47) | RAB9APOLBNPC1NR4A1MAPT | |
| SCHEMBL4696811 | 0.77 | HSD17B10 (0.47) | MAOARAB9APOLBNPC1MAPT | |
| SCHEMBL11754501 | 0.77 | ALDH1A1 (0.47) | RAB9APOLBNPC1MAPTHPGD | |
| SCHEMBL8720569 | 0.76 | ALDH1A1 (0.43) | RAB9APOLBNPC1MAPTMEN1 | |
| SCHEMBL3407682 | 0.75 | KDM4E (0.40) | MAPTHPGDLMNAKMT2AALDH1A1 | |
| SCHEMBL4328076 | 0.75 | DYRK1A (0.43) | RAB9APOLBMAPTMEN1LMNA | |
| SCHEMBL5782916 | 0.75 | ALDH1A1 (0.42) | RAB9APOLBNPC1TDP1MEN1 | |
| SCHEMBL5782169 | 0.75 | DYRK1A (0.43) | RAB9ANPC1MAPTLMNACYP1A2 | |
| SCHEMBL197626 | 0.75 | KDM4E (0.45) | RAB9ANPC1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6649604-B2 | Analgesics; antidiabetic agents; antiinflamamtory agents | AMGEN INC. | 2003-11-18 | — | — | US | disclosed |
| US-6420385-B1 | INFLAMMATORY, PAIN AND DIABETES DISEASES, | AMGEN INC. | 2002-07-16 | — | — | US | disclosed |