Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | CNR1 | P21554 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | F13A1 | P00488 | 1/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1223474 | 0.79 | CNR1 (0.68) | EPHX1LMNAGAATAAR1KMT2A | |
| SCHEMBL9798738 | 0.78 | KMT2A (0.55) | EPHX1GAAKMT2ANPC1RAB9A | |
| SCHEMBL667359 | 0.78 | KDM4E (0.65) | LMNAMAPTSMN1; SMN2KDM4EF13A1 | |
| SCHEMBL3654946 | 0.77 | CA2 (0.52) | EPHX1LMNAGAATAAR1KMT2A | |
| SCHEMBL9799589 | 0.75 | GLA (0.50) | GAATAAR1KMT2ANPC1RAB9A | |
| SCHEMBL6682075 | 0.74 | ST14 (0.45) | EPHX1LMNAGAATAAR1KMT2A | |
| SCHEMBL1979285 | 0.74 | KDM4E (0.46) | LMNAGAAKMT2ANPC1RAB9A | |
| SCHEMBL5186025 | 0.74 | KMT2A (0.57) | LMNAGAAKMT2ATSHRMEN1 | |
| SCHEMBL3407682 | 0.74 | KDM4E (0.40) | LMNAKMT2ACNR1MAPTSMN1; SMN2 | |
| SCHEMBL27475656 | 0.73 | CNR1 (0.68) | EPHX1KMT2ANPC1RAB9ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252604-B1 | THIAZOLE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R TECH UENO LTD (JP) | 2014-01-08 | — | — | EP | claimed |