SCHEMBL3408049

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3412138	0.83	PTGS2 (0.45)	PTGS2PSEN1PSEN2APH1BNCSTN
	SCHEMBL3408817	0.78	PTGS2 (0.46)	PTGS2PSEN1PSEN2APH1BNCSTN
	SCHEMBL8192595	0.75	LMNA (0.43)	PTGS2TRPV1TRPM8
	SCHEMBL3406069	0.72	PTGS2 (0.40)	PTGS2PSEN1PSEN2APH1BNCSTN
	SCHEMBL3408075	0.72	PSEN1 (0.47)	PTGS2PSEN1PSEN2APH1BNCSTN
	SCHEMBL4092365	0.71	PSEN1 (0.47)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL3412245	0.71	PSEN1 (0.54)	PTGS2PSEN1PSEN2APH1BNCSTN
	SCHEMBL3412354	0.71	PTGS2 (0.39)	PTGS2PSEN1PSEN2APH1BNCSTN
	SCHEMBL3408136	0.70	PSEN1 (0.41)	PTGS2PSEN1PSEN2APH1BNCSTN
	SCHEMBL3407309	0.69	PSEN1 (0.49)	PTGS2PSEN1PSEN2APH1BNCSTN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.