SCHEMBL340842

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL342354	0.98	HPGD (0.43)	NPC1RAB9AHPGDTP53USP2
	SCHEMBL341722	0.94	HCRTR1 (0.41)	NPC1RAB9AHPGDTP53USP2
	SCHEMBL341469	0.87	MMP1 (0.41)	NPC1RAB9AMMP1MMP9MMP13
	SCHEMBL340590	0.86	MEN1 (0.45)	ALDH1A1MMP1MMP9MMP13MEN1
	SCHEMBL2768143	0.86	HTR2A (0.45)	HTR2A
	SCHEMBL5109487	0.86	SIGMAR1 (0.43)	—
	SCHEMBL2769257	0.86	HTR2A (0.45)	HTR2A
	SCHEMBL341805	0.86	HTR2A (0.45)	HTR2A
	SCHEMBL339898	0.86	SIGMAR1 (0.43)	—
	SCHEMBL5112230	0.86	SIGMAR1 (0.43)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.