Sugi Predict

Sugi Predict / Compounds / Phenylpyruvate

Phenylpyruvate

Phenylpyruvate

SCHEMBL6850951

N.O=C(O)C(=O)Cc1ccccc1

nearest known ligand 0.95

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CES1 P23141 3/20 0.76
▸ CES2 O00748 2/20 0.76
▸ FNTA P49354 2/20 0.61
▸ FNTB P49356 2/20 0.61
▸ AKR1B1 P15121 1/20 0.61
▸ F2 P00734 2/20 0.55
▸ CTBP2 P56545 1/20 0.54
▸ PLG P00747 1/20 0.53
▸ PRSS1 P07477 1/20 0.53
▸ PRSS2 P07478 1/20 0.53
▸ C1S P09871 1/20 0.53
▸ PRSS3 P35030 1/20 0.53
▸ MEN1 O00255 1/20 0.52
▸ KMT2A Q03164 1/20 0.52
▸ HDAC8 Q9BY41 1/20 0.52
▸ HDAC6 Q9UBN7 1/20 0.52
▸ CYP3A4 P08684 1/20 0.50
▸ CYP2C9 P11712 1/20 0.50
▸ ALDH1A1 P00352 1/20 0.48
▸ MAPK1 P28482 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylpyruvate SCHEMBL43235 0.97 CES1 (0.80) CES1CES2FNTAFNTBAKR1B1
Phenylpyruvate SCHEMBL28203540 0.97 CES1 (0.80) CES1CES2FNTAFNTBAKR1B1
Phenylpyruvate SCHEMBL28233246 0.95 CES1 (0.76) CES1CES2FNTAFNTBAKR1B1
Phenylpyruvate SCHEMBL11193388 0.95 CES1 (0.76) CES1CES2FNTAFNTBAKR1B1
Phenylpyruvate SCHEMBL28233232 0.95 CES1 (0.76) CES1CES2FNTAFNTBAKR1B1
Phenylpyruvate SCHEMBL9217988 0.95 CES1 (0.76) CES1CES2FNTAFNTBAKR1B1
Phenylpyruvate SCHEMBL3408866 0.95 CES1 (0.76) CES1CES2FNTAFNTBAKR1B1
Phenylpyruvate SCHEMBL468389 0.95 CES1 (0.76) CES1CES2FNTAFNTBAKR1B1
Phenylpyruvate SCHEMBL27281240 0.95 CES1 (0.76) CES1CES2FNTAFNTBAKR1B1
Phenylpyruvate SCHEMBL28232350 0.95 CES1 (0.76) CES1CES2FNTAFNTBAKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109588554-A It is a kind of to utilize waste bamboo shell solid state fermentation production biological feedstuff and preparation method thereof 浙江皇冠科技有限公司 2019-04-09 — — CN claimed
CN-1138022-A Synthetic method of phenyl-pyruvic alkali salt and ammonium salt NANJING CHEMICAL ENGINEERING U (CN) 1996-12-18 — — CN claimed
CN-109588554-A It is a kind of to utilize waste bamboo shell solid state fermentation production biological feedstuff and preparation method thereof 浙江皇冠科技有限公司 2019-04-09 — — CN disclosed
CN-109588554-A It is a kind of to utilize waste bamboo shell solid state fermentation production biological feedstuff and preparation method thereof 浙江皇冠科技有限公司 2019-04-09 — — CN disclosed
US-6696266-B1 DIAGNOSING AND MONITORING LIVER INJURY OR FAILURE; SENSITIVE, ACCURATE, INEXPENSIVE MEASUREMENT IN BLOOD ASAHI KASEI PHARMA CORPORATION (JP) 2004-02-24 — — US disclosed
CN-1049650-C Synthetic method of phenyl-pyruvic alkali salt and ammonium salt NANJING CHEMICAL ENGINEERING U (CN) 2000-02-23 — — CN disclosed
CN-1138022-A Synthetic method of phenyl-pyruvic alkali salt and ammonium salt NANJING CHEMICAL ENGINEERING U (CN) 1996-12-18 — — CN disclosed
US-5420023-A From phenylpyruvic acid using Nocardia microorgansims KURARAY CO., LTD. (JP) 1995-05-30 — — US disclosed
EP-0215414-B1 PROCESS FOR PRODUCING L-PHENYLALANINE Kuraray Co., Ltd. (JP) 1991-11-21 — — EP disclosed
EP-0215414-A2 Process for producing L-phenylalanine Kuraray Co., Ltd. (JP) 1987-03-25 — — EP disclosed