Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LYPLA1 | O75608 | 3/20 | 0.40 |
| ▸ | LYPLA2 | O95372 | 3/20 | 0.40 |
| ▸ | HLCS | P50747 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15324595 | 1.00 | LYPLA1 (0.40) | LYPLA1LYPLA2HLCS | |
| SCHEMBL12370961 | 0.72 | LYPLA1 (0.59) | LYPLA1LYPLA2 | |
| SCHEMBL10555179 | 0.71 | LYPLA1 (0.50) | LYPLA1LYPLA2HLCS | |
| SCHEMBL3409872 | 0.71 | LYPLA1 (0.47) | LYPLA1LYPLA2 | |
| SCHEMBL3402991 | 0.63 | LYPLA1 (0.51) | LYPLA1LYPLA2 | |
| SCHEMBL15324179 | 0.62 | LYPLA1 (0.32) | LYPLA1LYPLA2 | |
| SCHEMBL3405253 | 0.62 | CYP1A2 (0.37) | LYPLA1LYPLA2HLCS | |
| SCHEMBL22618564 | 0.61 | CTRB1 (0.50) | — | |
| SCHEMBL14883105 | 0.59 | ALDH1A1 (0.39) | HLCS | |
| SCHEMBL21508603 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9521845-B2 | Beta-lactones as antibacterial agents | LUDWIG-MAXIMILIANS-UNIVERSITÄT-MÜNCHEN (DE) | 2016-12-20 | — | — | US | disclosed |
| US-20140163094-A1 | BETA-LACTONES AS ANTIBACTERIAL AGENTS | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2014-06-12 | — | — | US | disclosed |
| US-8669283-B2 | Beta-lactones as antibacterial agents | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2014-03-11 | — | — | US | disclosed |
| US-8563598-B2 | — | — | 2013-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140163094-A1 | BETA-LACTONES AS ANTIBACTERIAL AGENTS | ALG8, PGLS, GLA | LYPLA1 651/4885LYPLA2 1208/4885HLCS 482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.