Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.37 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.37 |
| ▸ | PLA2G2E | Q9NZK7 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.35 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3345462 | 0.92 | PLA2G2A (0.45) | ALDH1A1HPGDKDM4EHSD17B10POLB | |
| SCHEMBL3348099 | 0.89 | HPGD (0.41) | ALDH1A1HPGDKDM4EHSD17B10POLB | |
| SCHEMBL3348857 | 0.89 | PLA2G10 (0.46) | ALDH1A1HPGDKDM4EHSD17B10PKM | |
| SCHEMBL3344376 | 0.81 | PLA2G2A (0.55) | PKMPLA2G10PLA2G1BPLA2G2APLA2G5 | |
| SCHEMBL3345040 | 0.81 | PTGDR2 (0.39) | ALDH1A1KDM4EHSD17B10PKMPLA2G2A | |
| SCHEMBL3344745 | 0.80 | PTGDR2 (0.48) | ALDH1A1HPGDKDM4EHSD17B10PKM | |
| SCHEMBL3344729 | 0.79 | DDB1 (0.41) | ALDH1A1HPGDKDM4EHSD17B10POLB | |
| SCHEMBL3348700 | 0.79 | ALDH1A1 (0.41) | ALDH1A1HPGDKDM4EHSD17B10POLB | |
| SCHEMBL3345066 | 0.78 | TDP1 (0.43) | ALDH1A1HPGDKDM4EHSD17B10PKM | |
| SCHEMBL3345108 | 0.73 | ALDH1A1 (0.43) | ALDH1A1HPGDKDM4EHSD17B10PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010040989-A1 | QUINOLIN-2-ONE COMPOUNDS | ARGENTA ORAL THERAPEUTICS LIMITED (GB) | 2010-04-15 | — | — | WO | disclosed |