Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 7/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3404349 | 0.84 | IRAK4 (0.31) | IRAK4 | |
| SCHEMBL3404306 | 0.81 | LMNA (0.34) | IRAK4KDM4ENPC1RAB9AL3MBTL1 | |
| SCHEMBL3409576 | 0.79 | LIPE (0.36) | IRAK4POLBKDM4ENPC1RAB9A | |
| SCHEMBL3406420 | 0.78 | CA2 (0.36) | KDM4E | |
| SCHEMBL3403241 | 0.77 | KMT2A (0.33) | — | |
| SCHEMBL3406190 | 0.76 | IRAK4 (0.32) | IRAK4 | |
| SCHEMBL3405114 | 0.75 | NPC1 (0.46) | POLBKDM4ENPC1RAB9AHKDC1 | |
| SCHEMBL3409623 | 0.74 | ALDH1A1 (0.38) | L3MBTL1 | |
| SCHEMBL3402152 | 0.67 | NAALAD2 (0.37) | — | |
| SCHEMBL22445787 | 0.64 | KDM4E (0.46) | KDM4ENPC1RAB9AHKDC1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370260-B1 | AZOLES AS MALONYL-COA DECARBOXYLASE INHIBITORS USEFUL AS METABOLIC MODULATORS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2010-11-24 | — | — | EP | claimed |