Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.33 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Crotonic Acid SCHEMBL1519018 | 1.00 | ALDH1A1 (0.44) | ALDH1A1TSHRTP53EGLN1EGLN3 | |
| Fumaric Acid SCHEMBL2350872 | 0.87 | ALDH1A1 (0.53) | ALDH1A1TSHRTP53EGLN1EGLN3 | |
| Fumaric Acid SCHEMBL2350878 | 0.87 | ALDH1A1 (0.53) | ALDH1A1TSHRTP53EGLN1EGLN3 | |
| Fumaric Acid SCHEMBL5152407 | 0.87 | ALDH1A1 (0.53) | ALDH1A1TSHRTP53EGLN1EGLN3 | |
| Maleic Acid SCHEMBL2350870 | 0.87 | ALDH1A1 (0.53) | ALDH1A1TSHRTP53EGLN1EGLN3 | |
| Maleic Acid SCHEMBL2350866 | 0.87 | ALDH1A1 (0.53) | ALDH1A1TSHRTP53EGLN1EGLN3 | |
| Fumaric Acid SCHEMBL5152411 | 0.87 | ALDH1A1 (0.53) | ALDH1A1TSHRTP53EGLN1EGLN3 | |
| Crotonic Acid SCHEMBL3409845 | 0.85 | TSHR (0.38) | ALDH1A1TSHRTP53EGLN1EGLN3 | |
| Crotonic Acid SCHEMBL3409852 | 0.85 | TSHR (0.38) | ALDH1A1TSHRTP53EGLN1EGLN3 | |
| Fumaric Acid SCHEMBL4917909 | 0.84 | ALDH1A1 (0.52) | ALDH1A1TSHRTP53EGLN1EGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2265617-B1 | SOLVENTS | BIONIQS LTD (GB) | 2014-07-02 | — | — | EP | claimed |
| EP-2265617-A1 | SOLVENTS | Bioniqs Limited (GB) | 2010-12-29 | — | — | EP | claimed |
| WO-2009034329-A1 | SOLVENTS | BIONIQS LIMITED (GB) | 2009-03-19 | — | — | WO | claimed |
| EP-2265617-B1 | SOLVENTS | BIONIQS LTD (GB) | 2014-07-02 | — | — | EP | disclosed |
| EP-2265617-A1 | SOLVENTS | Bioniqs Limited (GB) | 2010-12-29 | — | — | EP | disclosed |
| WO-2009034329-A1 | SOLVENTS | BIONIQS LIMITED (GB) | 2009-03-19 | — | — | WO | disclosed |