Maleic Acid

Maleic Acid

SCHEMBL2350870

CCN(CC)CC.O=C(O)/C=C\C(=O)O

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2BTKCACNA1CCACNA1DCACNA1FCACNA1SCCR5CPT1BCPT2DPP4DRD1DRD2EGFRERBB2ERBB4HRH1HRH3HTR1AHTR2AHTR2BHTR2CHTR4JAK1JAK2JAK3MPLMTORPPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PPARGSLC6A2SLC6A3SLC6A4SMOTYK2pol

The experimentally established mechanism targets of Maleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.53
▸ TSHR P16473 4/20 0.53
▸ TP53 P04637 1/20 0.53
▸ EGLN1 Q9GZT9 1/20 0.53
▸ EGLN3 Q9H6Z9 1/20 0.53
▸ HCAR2 Q8TDS4 7/20 0.48
▸ GABRR1 P24046 2/20 0.38
▸ GABRR2 P28476 2/20 0.38
▸ BLM P54132 2/20 0.38
▸ GABRR3 A8MPY1 1/20 0.38
▸ LMNA P02545 1/20 0.38
▸ APEX1 P27695 1/20 0.38
▸ NPSR1 Q6W5P4 1/20 0.38
▸ TDP1 Q9NUW8 1/20 0.38
▸ GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fumaric Acid SCHEMBL2350878 1.00 ALDH1A1 (0.53) ALDH1A1TSHRTP53EGLN1EGLN3
Fumaric Acid SCHEMBL5152411 1.00 ALDH1A1 (0.53) ALDH1A1TSHRTP53EGLN1EGLN3
Fumaric Acid SCHEMBL2350872 1.00 ALDH1A1 (0.53) ALDH1A1TSHRTP53EGLN1EGLN3
Fumaric Acid SCHEMBL5152407 1.00 ALDH1A1 (0.53) ALDH1A1TSHRTP53EGLN1EGLN3
Maleic Acid SCHEMBL2350866 1.00 ALDH1A1 (0.53) ALDH1A1TSHRTP53EGLN1EGLN3
Fumaric Acid SCHEMBL4917909 0.97 ALDH1A1 (0.52) ALDH1A1TSHRTP53EGLN1EGLN3
Crotonic Acid SCHEMBL3410259 0.87 ALDH1A1 (0.44) ALDH1A1TSHRTP53EGLN1EGLN3
Crotonic Acid SCHEMBL1519018 0.87 ALDH1A1 (0.44) ALDH1A1TSHRTP53EGLN1EGLN3
Fumaric Acid SCHEMBL4917912 0.86 ALDH1A1 (0.44) ALDH1A1TSHRTP53EGLN1EGLN3
Fumaric Acid SCHEMBL4917905 0.86 ALDH1A1 (0.44) ALDH1A1TSHRTP53EGLN1EGLN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113113233-A Solid-liquid mixed winding type aluminum electrolytic capacitor and preparation method thereof 深圳市金富康电子有限公司 2021-07-13 — — CN claimed
EP-1519972-B2 COMPOSITIONS FOR PRODUCING AMINOPLAST PRODUCTS AND METHOD FOR PRODUCING PRODUCTS FROM THESE COMPOSITIONS BOREALIS AGROLINZ MELAMINE (AT) 2011-08-24 — — EP claimed
EP-1519972-B1 COMPOSITIONS FOR PRODUCING AMINOPLAST PRODUCTS AND METHOD FOR PRODUCING PRODUCTS FROM THESE COMPOSITIONS AMI AGROLINZ MELAMINE INT GMBH (AT) 2006-10-25 — — EP claimed
US-20050250896-A1 Compositions for producing aminoplast products and method for producing products from these compositions AMI-AGROLINZ MELAMINE INTERNATIONAL GMBH (AT) 2005-11-10 — — US claimed
JP-11186109-A — — None — — JP disclosed
CN-120865671-A SIS soap-free emulsion and preparation method and application thereof 北京化工大学 2025-10-31 — — CN disclosed
CN-120535851-A Soap-free emulsion of diene liquid rubber and preparation method and application thereof 北京化工大学 2025-08-26 — — CN disclosed
US-20250174409-A1 SOLID ELECTROLYTE CAPACITOR AND METHOD FOR MANUFACTURING SAME CARLIT CO., LTD. (JP) 2025-05-29 — — US disclosed
US-20250046527-A1 ELECTROLYTIC CAPACITOR NIPPON CHEMI-CON CORPORATION (JP) 2025-02-06 — — US disclosed
CN-118843914-A Solid electrolytic capacitor and method for manufacturing the same 佳里多股份公司 2024-10-25 — — CN disclosed
EP-4383295-A1 ELECTROLYTIC CAPACITOR Nippon Chemi-Con Corporation (JP) 2024-06-12 — — EP disclosed
CN-115347324-B Ceramic coating, separator comprising same and lithium ion battery 武汉微美新材料科技有限公司 2024-05-24 — — CN disclosed
EP-0033213-B1 PIGMENT DISPERSIONS CONTAINING COPOLYMER PIGMENT DISPERSANTS AND METHODS OF GRINDING PIGMENT DISPERSIONS HÜLS AMERICA INC. (a Delaware corporation) (US) 1984-06-13 — — EP disclosed
US-4310453-A Pigment dispersions containing copolymer of oxazolidinylalkyl or oxazolidinylalkoxyalkyl (meth)acrylate TENNECO CHEMICALS, INC. (US) 1982-01-12 — — US disclosed
EP-0033213-A2 Pigment dispersions containing copolymer pigment dispersants and methods of grinding pigment dispersions HÜLS AMERICA INC. (a Delaware corporation) (US) 1981-08-05 — — EP disclosed
US-3963730-A ACID CATALYST SANKYO COMPANY LIMITED (JA) 1976-06-15 — — US disclosed
US-3959295-A ACETONE WITH AMMONIA, ACID CATALYSTS CIBA-GEIGY CORPORATION (US) 1976-05-25 — — US disclosed
US-3959298-A ACETONINE WITH WATER IN ACID CATALYST SANKYO COMPANY LIMITED (JA) 1976-05-25 — — US disclosed
US-3953459-A Process for the preparation of 2,2,6,6-tetramethyl-4-oxopiperidine CIBA-GEIGY CORPORATION (US) 1976-04-27 — — US disclosed
US-3940353-A Pigment dispersions and lacquers containing copolymer of isobornyl methacrylate ROHM AND HAAS COMPANY (US) 1976-02-24 — — US disclosed
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