Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5571914 | 0.81 | CA1 (0.30) | — | |
| SCHEMBL3413205 | 0.81 | — | — | |
| SCHEMBL4252103 | 0.61 | MEN1 (0.31) | — | |
| SCHEMBL4974655 | 0.61 | MAPK1 (0.31) | — | |
| SCHEMBL17338110 | 0.60 | ALDH1A1 (0.36) | — | |
| SCHEMBL6946328 | 0.60 | ALDH1A1 (0.33) | — | |
| SCHEMBL10648555 | 0.59 | — | — | |
| SCHEMBL1219320 | 0.58 | — | — | |
| SCHEMBL874920 | 0.58 | ALOX15 (0.31) | — | |
| SCHEMBL6984958 | 0.58 | INMT (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2262789-A1 | 2-AMINOQUINOLINES | F. Hoffmann-La Roche AG (CH) | 2010-12-22 | — | — | EP | disclosed |
| WO-2009109477-A1 | 2-AMINOQUINOLINES | F. HOFFMANN-LA ROCHE AG (CH) | 2009-09-11 | — | — | WO | disclosed |