Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 16/20 | 0.43 |
| ▸ | SLC5A1 | P13866 | 11/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | PYGL | P06737 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3410780 | 1.00 | SLC5A2 (0.43) | SLC5A2SLC5A1ADORA2AADORA2BADORA3 | |
| SCHEMBL3413156 | 0.92 | SLC5A2 (0.44) | SLC5A2SLC5A1 | |
| SCHEMBL3413152 | 0.92 | SLC5A2 (0.44) | SLC5A2SLC5A1 | |
| SCHEMBL3406454 | 0.91 | SLC5A2 (0.40) | SLC5A2SLC5A1 | |
| SCHEMBL3411874 | 0.88 | SLC5A2 (0.50) | SLC5A2SLC5A1 | |
| SCHEMBL3411865 | 0.88 | SLC5A2 (0.50) | SLC5A2SLC5A1 | |
| SCHEMBL3406457 | 0.88 | SLC5A2 (0.54) | SLC5A2SLC5A1 | |
| SCHEMBL3411034 | 0.87 | SLC5A2 (0.40) | SLC5A2SLC5A1ADORA2AADORA2BADORA1 | |
| SCHEMBL3411037 | 0.87 | SLC5A2 (0.40) | SLC5A2SLC5A1ADORA2AADORA2BADORA1 | |
| SCHEMBL3410042 | 0.87 | SLC5A2 (0.43) | SLC5A2SLC5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099104-A1 | SUBSTITUTED INDAZOLES-O- GLUCOSIDES | PATEL MONA | 2009-04-16 | — | — | US | claimed |
| US-7084124-B2 | Substituted indazole-O-glucosides | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-08-01 | — | — | US | claimed |
| US-20050032711-A1 | Substituted indazole-O-glucosides | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-02-10 | — | — | US | claimed |
| US-7816331-B2 | Substituted indazole-O-glucosides | JANSSEN PHARMACEUTICA NV (BE) | 2010-10-19 | — | — | US | disclosed |
| US-20100062971-A1 | SUBSTITUTED INDAZOLE-O-GLUCOSIDES | PATEL MONA | 2010-03-11 | — | — | US | disclosed |
| US-20090099104-A1 | SUBSTITUTED INDAZOLES-O- GLUCOSIDES | PATEL MONA | 2009-04-16 | — | — | US | disclosed |
| US-7511021-B2 | Substituted indazole-O-glucosides | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-03-31 | — | — | US | disclosed |
| US-20060217323-A1 | Substituted indazole-O-glucosides | Tanabe Pharma Corporation (JP) | 2006-09-28 | — | — | US | disclosed |
| US-7084124-B2 | Substituted indazole-O-glucosides | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-08-01 | — | — | US | disclosed |
| US-20050032711-A1 | Substituted indazole-O-glucosides | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050032711-A1 | Substituted indazole-O-glucosides | GYS2, GPR119, UGGT1 | SLC5A2 10/4885SLC5A1 9/4885ADORA2A 4335/4885 |
| US-20100062971-A1 | SUBSTITUTED INDAZOLE-O-GLUCOSIDES | GYS2, GPR119, UGGT1 | SLC5A2 10/4885SLC5A1 9/4885ADORA2A 4335/4885 |
| US-20090099104-A1 | SUBSTITUTED INDAZOLES-O- GLUCOSIDES | GYS2, GPR119, PYGL | SLC5A2 10/4885SLC5A1 11/4885ADORA2A 4170/4885 |
| US-20060217323-A1 | Substituted indazole-O-glucosides | GYS2, GPR119, UGGT1 | SLC5A2 10/4885SLC5A1 9/4885ADORA2A 4335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.