Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3406757 | 0.77 | SOAT1 (0.51) | NLRP3 | |
| SCHEMBL10189418 | 0.75 | SOAT2 (0.48) | NLRP3 | |
| SCHEMBL3404773 | 0.74 | SOAT2 (0.36) | — | |
| SCHEMBL3410912 | 0.74 | NLRP3 (0.43) | NLRP3 | |
| SCHEMBL3404851 | 0.70 | NLRP3 (0.41) | NLRP3 | |
| SCHEMBL3409923 | 0.70 | SOAT2 (0.39) | NLRP3 | |
| SCHEMBL854439 | 0.69 | SOAT2 (0.47) | NLRP3 | |
| SCHEMBL855625 | 0.68 | SOAT2 (0.52) | — | |
| SCHEMBL3407860 | 0.68 | NLRP3 (0.59) | NLRP3 | |
| SCHEMBL3408628 | 0.67 | SOAT1 (0.54) | NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2200979-A1 | NOVEL DERIVATIVES OF PHENYLUREAS, INHIBITORS OF THE SOAT-1 ENZYME, PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM | Galderma Research & Development (FR) | 2010-06-30 | — | — | EP | disclosed |
| WO-2009030752-A1 | NOVEL DERIVATIVES OF PHENYLUREAS, INHIBITORS OF THE SOAT-1 ENZYME, PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2009-03-12 | — | — | WO | disclosed |