Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.72 |
| ▸ | MEN1 | O00255 | 3/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.44 |
| ▸ | CHRNG | P07510 | 1/20 | 0.44 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | CHRND | Q07001 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1919973 | 0.71 | KMT2A (0.60) | KMT2AMEN1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL3413245 | 0.70 | KMT2A (0.46) | KMT2AMEN1ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL634550 | 0.64 | SLC6A2 (0.60) | KMT2AMEN1ALDH1A1KDM4ECHRNA1 | |
| SCHEMBL13176761 | 0.62 | ATM (0.55) | KMT2AMEN1ALDH1A1HTTLMNA | |
| SCHEMBL21331278 | 0.62 | SLC6A2 (0.58) | KMT2AMEN1ALDH1A1KDM4ECHRNA1 | |
| SCHEMBL770607 | 0.62 | SLC6A3 (1.00) | KMT2AMEN1ALDH1A1CHRNA1CHRNG | |
| SCHEMBL697363 | 0.61 | TSHR (0.65) | KMT2AMEN1ALDH1A1KDM4ECHRNA1 | |
| SCHEMBL29619400 | 0.61 | TSHR (0.65) | KMT2AMEN1ALDH1A1KDM4ECHRNA1 | |
| SCHEMBL6755393 | 0.61 | KMT2A (0.46) | KMT2AMEN1ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL6755389 | 0.61 | KMT2A (0.46) | KMT2AMEN1ALDH1A1KDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100063118-A1 | Hydantoins Having RNase Modulatory Activity | WYETH (US) | 2010-03-11 | — | — | US | claimed |
| WO-2005090316-A1 | HYDANTOINS HAVING RNase MODULATORY ACTIVITY | WYETH (US) | 2005-09-29 | — | — | WO | claimed |
| US-20050203156-A1 | Hydantoins having RNase modulatory activity | WYETH (US) | 2005-09-15 | — | — | US | claimed |
| US-20100063118-A1 | Hydantoins Having RNase Modulatory Activity | WYETH (US) | 2010-03-11 | — | — | US | disclosed |
| WO-2005090316-A1 | HYDANTOINS HAVING RNase MODULATORY ACTIVITY | WYETH (US) | 2005-09-29 | — | — | WO | disclosed |
| US-20050203156-A1 | Hydantoins having RNase modulatory activity | WYETH (US) | 2005-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063118-A1 | Hydantoins Having RNase Modulatory Activity | RNASEH1, RNASE1, RNASEL | KMT2A 1205/4885MEN1 3802/4885ALDH1A1 1439/4885 |
| US-20050203156-A1 | Hydantoins having RNase modulatory activity | RNASEH1, RNASE1, RNASEL | KMT2A 1205/4885MEN1 3802/4885ALDH1A1 1439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.