SCHEMBL3411489

SCHEMBL3411489

CCN(CC)c1ccc(C(O)c2ccccc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 9/20 0.54
ALDH1A1 P00352 3/20 0.50
TSHR P16473 3/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
NOX1 Q9Y5S8 1/20 0.50
KDM4E B2RXH2 1/20 0.49
GLA P06280 1/20 0.49
GAA P10253 1/20 0.49
MAPT P10636 1/20 0.49
NR1H2 P55055 1/20 0.49
NR1H3 Q13133 1/20 0.49
HTT P42858 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
LMNA P02545 1/20 0.45
PSMD14 O00487 1/20 0.45
CYP3A4 P08684 1/20 0.45
MAPK1 P28482 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4116469 0.92 ALDH1A1 (0.56) CNR2ALDH1A1TSHRMEN1KMT2A
SCHEMBL27776204 0.84 CNR2 (0.53) CNR2ALDH1A1TSHRMEN1KMT2A
SCHEMBL109699 0.84 CNR2 (0.53) CNR2ALDH1A1TSHRMEN1KMT2A
SCHEMBL10355544 0.83 CNR2 (0.50) CNR2ALDH1A1TSHRMAPTPSMD14
SCHEMBL4314634 0.82 CNR2 (0.52) CNR2ALDH1A1TSHRMEN1KMT2A
SCHEMBL14283608 0.82 CNR2 (0.52) CNR2ALDH1A1TSHRMEN1KMT2A
SCHEMBL3890200 0.82 CNR2 (0.52) CNR2ALDH1A1TSHRMEN1KMT2A
SCHEMBL14283583 0.82 CNR2 (0.52) CNR2ALDH1A1TSHRMEN1KMT2A
SCHEMBL3432679 0.82 CNR2 (0.56) CNR2ALDH1A1MEN1KMT2AKDM4E
SCHEMBL77394 0.79 CNR2 (0.49) CNR2ALDH1A1TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111315762-B Optically controlled switch with affinity tag and method of use thereof 加利福尼亚大学董事会 2024-04-16 CN disclosed
CN-116669811-A Compositions and methods for enhancing visual function 加利福尼亚大学董事会 2023-08-29 CN disclosed
CN-111315762-A Light-operated switch with affinity label and use method thereof 加利福尼亚大学董事会 2020-06-19 CN disclosed
EP-2010294-B1 ANTIOXIDANTS MERCK PATENT GMBH (DE) 2015-12-02 EP disclosed
US-7906684-B2 Antioxidants MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-03-15 US disclosed
US-7906684-B2 Antioxidants MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-03-15 US disclosed
WO-2010151609-A1 PHOTOSWITCH-ENABLED ION CHANNEL ASSAY SYSTEM PHOTOSWITCH BIOSCIENCES INC. (US) 2010-12-29 WO disclosed
WO-2010051343-A1 PHOTOREACTIVE SYNTHETIC REGULATOR OF PROTEIN FUNCTION AND METHODS OF USE THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-05-06 WO disclosed
US-20090246158-A1 ANTIOXIDANTS MERCK PATENT GESELLSCHAFT (DE) 2009-10-01 US disclosed
US-20090246158-A1 ANTIOXIDANTS MERCK PATENT GESELLSCHAFT (DE) 2009-10-01 US disclosed
US-5250492-A Mixture of color former stabilized with complexing agent, color developer, pressure-rupturable microcapsules containing solvent THE STANDARD REGISTER COMPANY (US) 1993-10-05 US disclosed
US-RE30803-E Colorless recording paper SCOTT PAPER COMPANY (US) 1981-11-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090246158-A1 ANTIOXIDANTS LPO, GPX1, GPX4 CNR2 3792/4885ALDH1A1 408/4885TSHR 3664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.