Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.53 |
| ▸ | MAOB | P27338 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.53 |
| ▸ | ALPG | P10696 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23704523 | 0.81 | MAOA (0.44) | MAOAMAOBMAPTHPGDCA2 | |
| SCHEMBL11637378 | 0.74 | MAOA (0.52) | MAOAMAOBMAPTHPGDCA2 | |
| SCHEMBL9032568 | 0.73 | GPR3 (0.48) | MAOAMAOBMAPTHPGDCA2 | |
| SCHEMBL869986 | 0.71 | GPR3 (0.40) | MAOAMAOBMAPTHPGDCA2 | |
| SCHEMBL23240 | 0.71 | GPR3 (0.40) | MAOAMAOBMAPTHPGDCA2 | |
| SCHEMBL3724121 | 0.71 | ESR2 (0.39) | MAOAMAPTHPGDALDH1A1HSD17B10 | |
| SCHEMBL5541064 | 0.71 | MAOA (0.63) | MAOAMAOBMAPTHPGDCA2 | |
| SCHEMBL1091708 | 0.71 | MAOA (0.48) | MAOAMAOBMAPTHPGDCA2 | |
| SCHEMBL1092088 | 0.71 | MAPT (0.44) | MAOAMAOBMAPTHPGDCA2 | |
| SCHEMBL2641278 | 0.71 | MAPT (0.48) | MAOAMAOBMAPTHPGDCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 293 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2887940-B1 | INHIBITORS OF CRL4 UBIQUITIN LIGASE AND USES THEREOF | UNIV CORNELL (US) | 2019-06-05 | — | — | EP | claimed |
| US-20150196546-A1 | INHIBITORS OF CRL4 UBIQUITIN LIGASE AND USES THEREOF | CORNELL UNIVERSITY | 2015-07-16 | — | — | US | claimed |
| EP-2887940-A2 | INHIBITORS OF CRL4 UBIQUITIN LIGASE AND USES THEREOF | Cornell University (US) | 2015-07-01 | — | — | EP | claimed |
| WO-2014031759-A2 | INHIBITORS OF CRL4 UBIQUITIN LIGASE AND USES THEREOF | CORNELL UNIVERSITY (US) | 2014-02-27 | — | — | WO | claimed |
| JP-5339110-A | — | — | None | — | — | JP | disclosed |
| JP-60006680-A | — | — | None | — | — | JP | disclosed |
| US-12630504-B2 | Phenethylamine derivatives, compositions, and methods of use | CYBIN IRL LIMITED (IE) | 2026-05-19 | — | — | US | disclosed |
| US-20240317704-A1 | PHENETHYLAMINE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE | CYBIN IRL LIMITED (IE) | 2024-09-26 | — | — | US | disclosed |
| EP-3555078-B1 | BISARYL HETEROCYCLES AS NRF2 ACTIVATORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2024-03-27 | — | — | EP | disclosed |
| EP-3367820-B1 | PREPARATION OF MODIFIED CELLULOSE AND ITS DERIVATIVES | INNOTECH MAT LLC (US) | 2024-01-24 | — | — | EP | disclosed |
| EP-4200290-A1 | PHENETHYLAMINE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE | Cybin IRL Limited (IE) | 2023-06-28 | — | — | EP | disclosed |
| EP-3224263-B1 | USE OF UBIQUITIN-PROTEASOME SYSTEM INHIBITORS FOR TREATMENT OF TUMORS ASSOCIATED WITH NEUROFIBROMATOSIS TYPE-2 | BIOXCEL LLC (US) | 2023-05-17 | — | — | EP | disclosed |
| JP-H05339110-A | WATER PEST CONTROL AGENT | ASAHI DENKA KOGYO KK | 1993-12-21 | — | — | JP | disclosed |
| EP-0278915-B1 | DIPHENYLETHYLENE DERIVATIVES | CIBA-GEIGY AG (CH) | 1991-11-27 | — | — | EP | disclosed |
| US-4876270-A | INSECTICIDES, MITICIDES, PARASITICIDES | CIBA-GEIGY CORPORATION (US) | 1989-10-24 | — | — | US | disclosed |
| US-4871762-A | CARDIOVASCULAR DISORDERS, ANTIALLERGENS | SANKYO COMPANY, LIMITED (JP) | 1989-10-03 | — | — | US | disclosed |
| EP-0278915-A2 | Diphenylethylene derivatives | CIBA-GEIGY AG (CH) | 1988-08-17 | — | — | EP | disclosed |
| US-4691027-A | FOR TREATING CICULATORY DISORDERS AND ALLERGIES | SANKYO COMPANY, LIMITED (JP) | 1987-09-01 | — | — | US | disclosed |
| EP-0157603-A2 | 1, 3-Benzoxathiole derivatives, their use and their preparation | SANKYO COMPANY LIMITED (JP) | 1985-10-09 | — | — | EP | disclosed |
| JP-S606680-A | BENZOXATHIOL-2-ONE DERIVATIVE AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE | SHOWA DENKO KK | 1985-01-14 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240317704-A1 | PHENETHYLAMINE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE | HTR2C, HTR2A, PNMT | MAOA 215/4885MAOB 318/4885MAPT 188/4885 |
| US-12630504-B2 | Phenethylamine derivatives, compositions, and methods of use | HTR2C, HTR1A, HTR2A | MAOA 144/4885MAOB 216/4885MAPT 821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.