Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.43 |
| ▸ | KDM5A | P29375 | 4/20 | 0.42 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | DGKA | P23743 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | POLA1 | P09884 | 1/20 | 0.40 |
| ▸ | PAM | P19021 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ICMT | O60725 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27674793 | 0.91 | DGKA (0.50) | DNM1DGKATSHRLMNAPOLB | |
| SCHEMBL28099338 | 0.91 | DGKA (0.50) | DNM1DGKATSHRLMNAPOLB | |
| SCHEMBL3410982 | 0.84 | DGKA (0.53) | DNM1KDM5APHF8KDM4CDGKA | |
| SCHEMBL27158034 | 0.84 | ALDH1A1 (0.43) | DGKATSHRLMNAPOLBPOLA1 | |
| SCHEMBL11654842 | 0.83 | TERT (0.53) | DGKALMNAPOLBMAPT | |
| SCHEMBL3412676 | 0.82 | DGKA (0.52) | DNM1KDM5APHF8KDM4CDGKA | |
| SCHEMBL5954671 | 0.82 | DGKA (0.55) | DGKATSHRLMNAPOLBPOLA1 | |
| SCHEMBL5954675 | 0.82 | DGKA (0.55) | DGKATSHRLMNAPOLBPOLA1 | |
| SCHEMBL1304408 | 0.82 | DGKA (0.55) | DGKATSHRLMNAPOLBPOLA1 | |
| SCHEMBL5308542 | 0.82 | DGKA (0.55) | DGKATSHRLMNAPOLBPOLA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2265617-A1 | SOLVENTS | Bioniqs Limited (GB) | 2010-12-29 | — | — | EP | disclosed |
| WO-2009034329-A1 | SOLVENTS | BIONIQS LIMITED (GB) | 2009-03-19 | — | — | WO | disclosed |