Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.51 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.51 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.51 |
| ▸ | GRM5 | P41594 | 2/20 | 0.49 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 2/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9021665 | 0.90 | KDM4E (0.61) | ALDH1A1KDM4EHPGDHTTL3MBTL1 | |
| SCHEMBL13986853 | 0.88 | KDM4E (0.59) | ALDH1A1KDM4EHPGDHTTL3MBTL1 | |
| SCHEMBL25779927 | 0.87 | GABRA1 (0.59) | ALDH1A1KDM4EHPGDHTTL3MBTL1 | |
| SCHEMBL9022425 | 0.86 | KDM4E (0.58) | ALDH1A1KDM4EHPGDHTTL3MBTL1 | |
| SCHEMBL9024311 | 0.84 | KDM4E (0.56) | ALDH1A1KDM4EHPGDHTTL3MBTL1 | |
| SCHEMBL18462119 | 0.84 | KDM4E (0.50) | ALDH1A1KDM4EHPGDHTTL3MBTL1 | |
| SCHEMBL17117019 | 0.83 | KDM1A (0.50) | ALDH1A1KDM4EHPGDHTTL3MBTL1 | |
| SCHEMBL31172969 | 0.83 | GRM5 (0.54) | ALDH1A1KDM4EHPGDHTTL3MBTL1 | |
| SCHEMBL995794 | 0.83 | GRM5 (0.54) | ALDH1A1KDM4EHPGDHTTL3MBTL1 | |
| SCHEMBL2434679 | 0.82 | KDM4E (0.51) | ALDH1A1KDM4EHPGDHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115710219-B | Method for preparing meta-cyano-substituted pyridine compound | 南开大学 | 2024-12-03 | — | — | CN | disclosed |
| EP-4273948-A1 | ORGANIC LIGHT EMITTING DIODE AND DEVICE COMPRISING THE SAME | Novaled GmbH (DE) | 2023-11-08 | — | — | EP | disclosed |
| US-20230348509-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2023-11-02 | — | — | US | disclosed |
| US-20230345811-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2023-10-26 | — | — | US | disclosed |
| US-20230292595-A1 | Organic Light Emitting Diode and Device Comprising the Same | NOVALED GMBH (DE) | 2023-09-14 | — | — | US | disclosed |
| US-20230292595-A1 | Organic Light Emitting Diode and Device Comprising the Same | NOVALED GMBH (DE) | 2023-09-14 | — | — | US | disclosed |
| US-20230270004-A1 | Organic Light Emitting Diode and Device Comprising the Same | NOVALED GMBH (DE) | 2023-08-24 | — | — | US | disclosed |
| US-20230270004-A1 | Organic Light Emitting Diode and Device Comprising the Same | NOVALED GMBH (DE) | 2023-08-24 | — | — | US | disclosed |
| US-20230263049-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2023-08-17 | — | — | US | disclosed |
| US-20230225201-A1 | Organic Light Emitting Diode and Device Comprising the Same | NOVALED GMBH (DE) | 2023-07-13 | — | — | US | disclosed |
| EP-1401434-B1 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS (PPAR) | LILLY CO ELI (US) | 2006-11-15 | — | — | EP | disclosed |
| EP-1687299-A1 | HETEROCYCLIC COMPOUNDS AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS, USEFUL FOR THE TREAMTMENT AND/OR PREVENTION OF DISORDERS MODULATED BY A PPAR | ELI LILLY AND COMPANY (US) | 2006-08-09 | — | — | EP | disclosed |
| US-20060167040-A1 | Pyrazolopyridine derivates | J. URIACH Y COMPANIA S.A. (ES) | 2006-07-27 | — | — | US | disclosed |
| WO-2005051945-A1 | HETEROCYCLIC COMPOUNDS AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS, USEFUL FOR THE TREATMENT AND/OR PREVENTION OF DISORDERS MODULATED BY A PPAR | ELI LILLY AND COMPANY (US) | 2005-06-09 | — | — | WO | disclosed |
| US-20050075378-A1 | Modulators of peroxisome proliferator activated receptors (ppar) | ELI LILLY AND COMPANY | 2005-04-07 | — | — | US | disclosed |
| CN-1578659-A | Modulators of peroxisome proliferator activated receptors (ppar) | LILLY CO ELI (US) | 2005-02-09 | — | — | CN | disclosed |
| EP-1401434-A1 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS (PPAR) | ELI LILLY AND COMPANY (US) | 2004-03-31 | — | — | EP | disclosed |
| US-6603007-B1 | Intermediates in the fields of pharmaceuticals, agrichemicals, ligands, silver halide photosensitive materials, liquid crystals, surfactants, electrophotography and organic electroluminescence | SANKIO CHEMICAL CO., LTD. (JP) | 2003-08-05 | — | — | US | disclosed |
| WO-2002100403-A1 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS (PPAR) | ELI LILLY AND COMPANY (US) | 2002-12-19 | — | — | WO | disclosed |
| EP-1231207-A1 | NOVEL BIPYRIDYL DERIVATIVES | Sankio Chemical Co., Ltd. (JP) | 2002-08-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075378-A1 | Modulators of peroxisome proliferator activated receptors (ppar) | PPARG, PPARA, PPARD | ALDH1A1 1363/4885KDM4E 4175/4885HPGD 283/4885 |
| US-20060167040-A1 | Pyrazolopyridine derivates | MAPK1, MAP4K2, MAP4K3 | ALDH1A1 789/4885KDM4E 3384/4885HPGD 414/4885 |
| US-20230263049-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | OSBPL3, OCIAD1, OSBP | ALDH1A1 480/4885KDM4E 3488/4885HPGD 1053/4885 |
| US-20230348509-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | MLX, OCIAD1, LBR | ALDH1A1 1681/4885KDM4E 2688/4885HPGD 3100/4885 |
| US-20230345811-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | OPRD1, L1CAM, OPRM1 | ALDH1A1 2748/4885KDM4E 4161/4885HPGD 3828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.