SCHEMBL3415214

SCHEMBL3415214

C#CCN(C(C)=O)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.49
TSHR P16473 3/20 0.48
GLA P06280 1/20 0.48
MEN1 O00255 5/20 0.46
KMT2A Q03164 5/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
POLQ O75417 1/20 0.46
CYP3A4 P08684 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
LTB4R2 Q9NPC1 1/20 0.44
TP53 P04637 2/20 0.43
HTT P42858 1/20 0.43
TSPO P30536 1/20 0.42
LMNA P02545 2/20 0.42
USP2 O75604 1/20 0.42
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
PYCR1 P32322 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10778940 0.81 POLQ (0.46) ALDH1A1TSHRGLAMEN1KMT2A
SCHEMBL10784051 0.81 POLQ (0.46) ALDH1A1TSHRGLAMEN1KMT2A
SCHEMBL200192 0.81 ALDH1A1 (0.49) ALDH1A1TSHRGLAMEN1KMT2A
SCHEMBL28381203 0.80 ADRA2C (0.54) ALDH1A1TSHRGLAMEN1KMT2A
SCHEMBL11802790 0.80 POLQ (0.51) ALDH1A1TSHRGLAMEN1KMT2A
SCHEMBL11664885 0.79 RAB9A (0.60) ALDH1A1TSHRGLAMEN1KMT2A
SCHEMBL5885580 0.78 KCNN4 (0.40) ALDH1A1MEN1KMT2ASMN1; SMN2HTT
SCHEMBL10099720 0.78 MEN1 (0.62) ALDH1A1TSHRGLAMEN1KMT2A
SCHEMBL27420679 0.77 POLQ (0.43) ALDH1A1TSHRGLAMEN1KMT2A
SCHEMBL23113822 0.77 MEN1 (0.45) ALDH1A1TSHRGLAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0044482-B1 N-ALLENYLALKYL-ACETANILIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES BAYER AG (DE) 1983-11-16 EP claimed
EP-0070456-A1 Sulfinyl- and sulfonyl-acetanilide derivatives, process for their preparation and their use as fungicides BAYER AG (DE) 1983-01-26 EP claimed
EP-0056589-A1 N-substituted anilides, process for their preparation and their use as fungicides BAYER AG (DE) 1982-07-28 EP claimed
EP-0018509-B1 N-ALLENYL ACETANILIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES BAYER AG (DE) 1982-05-19 EP claimed
EP-0044482-A2 N-allenylalkyl-acetanilides, process for their preparation and their use as fungicides BAYER AG (DE) 1982-01-27 EP claimed
EP-0020859-A1 Substituted N-allyl acetanilides, process for their preparation and their use as fungicides BAYER AG (DE) 1981-01-07 EP claimed
EP-0018509-A1 N-Allenyl acetanilides, process for their preparation and their use as fungicides BAYER AG (DE) 1980-11-12 EP claimed
EP-1934175-B1 ANTI-HYPERCHOLESTEROLEMIC COMPOUNDS MERCK SHARP & DOHME (US) 2010-11-17 EP disclosed
US-4416889-A Combating fungi with N-allenyl-acetanilides BAYER AKTIENGESELLSCHAFT (DE) 1983-11-22 US disclosed
EP-0044482-B1 N-ALLENYLALKYL-ACETANILIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES BAYER AG (DE) 1983-11-16 EP disclosed
EP-0019858-B1 N-OXIMINOALKYL ANILIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES BAYER AG (DE) 1983-06-22 EP disclosed
US-4385069-A Combating fungi with N-allenyl-acetanilides BAYER AKTIENGESELLSCHAFT (DE) 1983-05-24 US disclosed
EP-0070456-A1 Sulfinyl- and sulfonyl-acetanilide derivatives, process for their preparation and their use as fungicides BAYER AG (DE) 1983-01-26 EP disclosed
EP-0018509-B1 N-ALLENYL ACETANILIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES BAYER AG (DE) 1982-05-19 EP disclosed
EP-0044482-A2 N-allenylalkyl-acetanilides, process for their preparation and their use as fungicides BAYER AG (DE) 1982-01-27 EP disclosed
EP-0044482-A2 N-allenylalkyl-acetanilides, process for their preparation and their use as fungicides BAYER AG (DE) 1982-01-27 EP disclosed
EP-0020859-A1 Substituted N-allyl acetanilides, process for their preparation and their use as fungicides BAYER AG (DE) 1981-01-07 EP disclosed
EP-0019858-A2 N-Oximinoalkyl anilides, process for their preparation and their use as fungicides BAYER AG (DE) 1980-12-10 EP disclosed
EP-0018509-A1 N-Allenyl acetanilides, process for their preparation and their use as fungicides BAYER AG (DE) 1980-11-12 EP disclosed
EP-0018509-A1 N-Allenyl acetanilides, process for their preparation and their use as fungicides BAYER AG (DE) 1980-11-12 EP disclosed