Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195079 | 0.73 | LMNA (0.47) | LMNAABCC4GAATSHRPTGS1 | |
| SCHEMBL340184 | 0.71 | KMT2A (0.49) | LMNAABCC4GAATSHRPTGS1 | |
| SCHEMBL339395 | 0.71 | ALDH1A1 (0.56) | LMNAABCC4GAATSHRPTGS1 | |
| SCHEMBL340407 | 0.67 | L3MBTL1 (0.46) | MEN1KMT2AALDH1A1HDAC1FFAR1 | |
| SCHEMBL341410 | 0.66 | KMT2A (0.36) | LMNAGAAMEN1KMT2AHDAC1 | |
| SCHEMBL340091 | 0.65 | MEN1 (0.55) | MEN1KMT2AHDAC1KDM4EMAPT | |
| SCHEMBL7904968 | 0.65 | SMN1; SMN2 (0.78) | LMNAABCC4GAATSHRPTGS1 | |
| SCHEMBL29581028 | 0.65 | LMNA (0.44) | LMNAABCC4GAATSHRPTGS1 | |
| SCHEMBL20661665 | 0.65 | ABCC4 (0.52) | LMNAABCC4GAATSHRPTGS1 | |
| SCHEMBL5171029 | 0.65 | ABCC4 (0.52) | LMNAABCC4GAATSHRPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9181175-B2 | Process for manufacture and resolution of 2-acylamino-3-diphenylpropanoic acid | Zhejiang Jiuzhous Pharmaceutical Co., Ltd. (CN) | 2015-11-10 | — | — | US | disclosed |
| EP-2387558-B1 | PROCESS FOR MANUFACTURE AND RESOLUTION OF 2-ACYLAMINO-3-DIPHENYLPROPANOIC ACID | ZHEJIANG JIUZHOU PHARM CO LTD (CN) | 2014-08-27 | — | — | EP | disclosed |
| US-20140179947-A1 | PROCESS FOR MANUFACTURE AND RESOLUTION OF 2-ACYLAMINO-3-DIPHENYLPROPANOIC ACID | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD. (CN) | 2014-06-26 | — | — | US | disclosed |
| US-8703990-B2 | Process for manufacture and resolution of 2-acylamino-3-diphenylpropanoic acid | Zhejiang Jiuzhous Pharmaceutical Co., Ltd. (CN) | 2014-04-22 | — | — | US | disclosed |
| US-20120016151-A1 | PROCESS FOR MANUFACTURE AND RESOLUTION OF 2-ACYLAMINO-3-DIPHENYLPROPANOIC ACID | NOVARTIS AG (CH) | 2012-01-19 | — | — | US | disclosed |
| EP-2387558-A1 | PROCESS FOR MANUFACTURE AND RESOLUTION OF 2-ACYLAMINO-3-DIPHENYLPROPANOIC ACID | Zhejiang Jiuzhou Pharmaceutical Co., Ltd. (CN) | 2011-11-23 | — | — | EP | disclosed |
| US-20110253230-A1 | Temperature Sensitive Valve Having Shape Memory Actuator | OMNITEK PARTNERS LLC (US) | 2011-10-20 | — | — | US | disclosed |
| WO-2010081410-A1 | PROCESS FOR MANUFACTURE AND RESOLUTION OF 2-ACYLAMINO-3-DIPHENYLPROPANOIC ACID | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD. (CN) | 2010-07-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179947-A1 | PROCESS FOR MANUFACTURE AND RESOLUTION OF 2-ACYLAMINO-3-DIPHENYLPROPANOIC ACID | DNPEP, MME, DPP7 | LMNA 1839/4885ABCC4 3526/4885GAA 37/4885 |
| US-20120016151-A1 | PROCESS FOR MANUFACTURE AND RESOLUTION OF 2-ACYLAMINO-3-DIPHENYLPROPANOIC ACID | DNPEP, MME, DPP7 | LMNA 1839/4885ABCC4 3526/4885GAA 37/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.