SCHEMBL3415845

SCHEMBL3415845

Cc1c(C)c(C)c2c(nnn2C(CCCc2ccc(O)cc2)n2nnc3c(C)c(C)c(C)c(C)c32)c1C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ESR1 P03372 4/20 0.36
▸ ADRA2A P08913 2/20 0.36
▸ ADORA3 P0DMS8 2/20 0.36
▸ TACR2 P21452 2/20 0.36
▸ SLC6A2 P23975 2/20 0.36
▸ SLC6A4 P31645 2/20 0.36
▸ SLC6A3 Q01959 2/20 0.36
▸ KDM4E B2RXH2 2/20 0.36
▸ ALDH1A1 P00352 2/20 0.36
▸ LMNA P02545 1/20 0.36
▸ SHBG P04278 1/20 0.36
▸ TP53 P04637 1/20 0.36
▸ CYP3A4 P08684 1/20 0.36
▸ HSPD1 P10809 1/20 0.36
▸ ADRB3 P13945 1/20 0.36
▸ HTR2C P28335 1/20 0.36
▸ HSPE1 P61604 1/20 0.36
▸ HIF1A Q16665 1/20 0.36
▸ TST Q16762 1/20 0.36
▸ HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2872821 0.76 ESR1 (0.41) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL104946 0.63 ESR1 (0.55) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL21698806 0.63 ESR1 (0.59) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL692205 0.62 ESR1 (0.53) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL28797212 0.62 ESR1 (0.63) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL9861541 0.61 ESR1 (0.56) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL28358797 0.61 ESR1 (0.57) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL983854 0.61 ESR1 (0.57) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL31745134 0.60 ESR1 (0.47) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL17206940 0.60 ESR1 (0.55) ESR1ADRA2AADORA3TACR2SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022190965-A1 BEAUTY METHOD 株式会社 資生堂 2022-09-15 — — WO claimed
EP-1468674-B1 Aqueous sunscreen composition containing at least an amphiphilic polymer of acrylamido 2-methyl-propane sulfonic acid and a water soluble silicone, uses thereof OREAL (FR) 2009-11-11 — — EP claimed
EP-1187598-B1 MICROPIGMENT MIXTURE BASF SE (DE) 2009-10-21 — — EP claimed
US-11952492-B2 Biodegradable, controlled release microcapsules ENCAPSYS, LLC (US) 2024-04-09 — — US disclosed
EP-4247537-A1 BIODEGRADABLE, CONTROLLED RELEASE MICROCAPSULES Encapsys, LLC (US) 2023-09-27 — — EP disclosed
US-11717471-B2 Hydrogel microcapsules ISP INVESTMENTS LLC (US) 2023-08-08 — — US disclosed
EP-4167929-A1 METHOD FOR PRODUCING A PERSONALIZED COSMETIC PREPARATION BASF SE (DE) 2023-04-26 — — EP disclosed
WO-2022190965-A1 BEAUTY METHOD 株式会社 資生堂 2022-09-15 — — WO disclosed
WO-2022109163-A1 BIODEGRADABLE, CONTROLLED RELEASE MICROCAPSULES ENCAPSYS, LLC (US) 2022-05-27 — — WO disclosed
US-20220162444-A1 BIODEGRADABLE, CONTROLLED RELEASE MICROCAPSULES ENCAPSYS, LLC (US) 2022-05-26 — — US disclosed
US-20220096337-A1 COSMETIC COMPOSITION OF LIQUID CRYSTAL LIPID PARTICLES FOR PERSONAL CARE APPLICATIONS BASF SE (DE) 2022-03-31 — — US disclosed
EP-2179986-A1 Mixtures of alkylsulfosuccinates and their use Cognis IP Management GmbH (DE) 2010-04-28 — — EP disclosed
EP-2116221-A1 Cosmetic preparation containing hydrocarbons Cognis IP Management GmbH (DE) 2009-11-11 — — EP disclosed
EP-2111847-A1 Hydrocarbon mixtures and their use Cognis IP Management GmbH (DE) 2009-10-28 — — EP disclosed
EP-1187598-B1 MICROPIGMENT MIXTURE BASF SE (DE) 2009-10-21 — — EP disclosed
EP-1762217-A1 Sunscreen composition comprising PPG-3 Benzyl Ether Myristate Beiersdorf AG (DE) 2007-03-14 — — EP disclosed
EP-1541136-A1 UV light-stable semi-solid transdermal systems comprising a photosensitive active agent and an UV-absorbing component Schering AG (DE) 2005-06-15 — — EP disclosed
US-20030165443-A1 Composition containing a dibenzoylmethane derivative and an alpha-alkylstyrene dimer uv stabilising method L'OREAL (FR) 2003-09-04 — — US disclosed
EP-1187598-A1 MICROPIGMENT MIXTURE Ciba SC Holding AG (CH) 2002-03-20 — — EP disclosed
WO-2000078277-A1 MICROPIGMENT MIXTURE CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-12-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11717471-B2 Hydrogel microcapsules MITF, DSG1, SHH ESR1 4670/4885ADRA2A 4410/4885ADORA3 4862/4885
US-20220096337-A1 COSMETIC COMPOSITION OF LIQUID CRYSTAL LIPID PARTICLES FOR PERSONAL CARE APPLICATIONS CUTA, LIPA, PLIN5 ESR1 4751/4885ADRA2A 3572/4885ADORA3 3981/4885
US-20030165443-A1 Composition containing a dibenzoylmethane derivative and an alpha-alkylstyrene dimer uv stabilising method DSG1, DDT, CUTA ESR1 4096/4885ADRA2A 2830/4885ADORA3 3014/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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