Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 3/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL250295 | 0.70 | LMNA (0.43) | — | |
| SCHEMBL250296 | 0.70 | LMNA (0.43) | — | |
| SCHEMBL4139935 | 0.64 | ALDH1A1 (0.43) | — | |
| SCHEMBL19791018 | 0.63 | — | — | |
| SCHEMBL19584807 | 0.60 | ALDH1A1 (0.40) | — | |
| SCHEMBL8893372 | 0.59 | RIPK1 (0.38) | DPP4DPP7 | |
| SCHEMBL20766934 | 0.58 | ICMT (0.44) | — | |
| SCHEMBL25538037 | 0.58 | SRC (0.44) | — | |
| SCHEMBL31021773 | 0.58 | ALDH1A1 (0.40) | — | |
| SCHEMBL28903495 | 0.57 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012003477-A2 | INHIBITION OF INFLAMMATION BYSIMULTANEOUS BLOCKADE OF MULTIPLE PROSTANOID RECEPTORS | ALLERGAN, INC. (US) | 2012-01-05 | — | — | WO | disclosed |