Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.62 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.56 |
| ▸ | HNF4A | P41235 | 1/20 | 0.53 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | FABP3 | P05413 | 1/20 | 0.49 |
| ▸ | FABP4 | P15090 | 1/20 | 0.49 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18759613 | 0.89 | HNF4A (0.63) | HNF4ABCAT2ALDH1A1LTB4R2ALOX15 | |
| SCHEMBL30292805 | 0.89 | HNF4A (0.63) | HNF4ABCAT2ALDH1A1LTB4R2ALOX15 | |
| SCHEMBL11554621 | 0.87 | HNF4A (0.61) | SLC6A3HNF4ABCAT2ALDH1A1LTB4R2 | |
| SCHEMBL10629615 | 0.86 | SLC6A3 (0.64) | SLC6A3AKR1C3HNF4ABCAT2AKR1C2 | |
| SCHEMBL32677772 | 0.85 | HNF4A (0.64) | HNF4ABCAT2ALDH1A1LTB4R2ALOX15 | |
| SCHEMBL32677769 | 0.85 | HNF4A (0.64) | HNF4ABCAT2ALDH1A1LTB4R2ALOX15 | |
| SCHEMBL505412 | 0.85 | HNF4A (0.64) | HNF4ABCAT2ALDH1A1LTB4R2ALOX15 | |
| Benzene SCHEMBL1403559 | 0.85 | HNF4A (0.69) | HNF4ABCAT2ALDH1A1LTB4R2ALOX15 | |
| SCHEMBL133057 | 0.85 | HNF4A (0.69) | HNF4ABCAT2ALDH1A1LTB4R2ALOX15 | |
| Benzene SCHEMBL28480917 | 0.85 | HNF4A (0.69) | HNF4ABCAT2ALDH1A1LTB4R2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2167077-A2 | ARYL/HETARYLAMIDES AS MODULATORS OF THE EP2 RECEPTOR | Bayer Schering Pharma Aktiengesellschaft (DE) | 2010-03-31 | — | — | EP | claimed |
| EP-2149551-A1 | N-(indol-3-ylalkyl)-(hetero)arylamid derivatives as modulators of EP2 receptors | Bayer Schering Pharma AG (DE) | 2010-02-03 | — | — | EP | claimed |
| US-20090023741-A1 | ARYL/HETARYLAMIDES AS MODULATORS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AG (DE) | 2009-01-22 | — | — | US | claimed |
| WO-2008152099-A2 | ARYL/HETARYLAMIDES AS MODULATORS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-12-18 | — | — | WO | claimed |
| EP-2002834-A1 | Aryl and hetaryl amides as modulators of EP2 receptors | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-12-17 | — | — | EP | claimed |
| CN-110862368-B | Photocatalytic oxidation synthesis method of benzocoumarin compound | 浙江工业大学 | 2021-06-15 | — | — | CN | disclosed |
| CN-110862368-A | Photocatalytic oxidation synthesis method of benzocoumarin compound | 浙江工业大学 | 2020-03-06 | — | — | CN | disclosed |
| EP-2167077-A2 | ARYL/HETARYLAMIDES AS MODULATORS OF THE EP2 RECEPTOR | Bayer Schering Pharma Aktiengesellschaft (DE) | 2010-03-31 | — | — | EP | disclosed |
| US-7625932-B2 | Pyrrole and pyrazole derivatives as potentiators of glutamate receptors | ELI LILLY AND COMPANY (US) | 2009-12-01 | — | — | US | disclosed |
| US-7625932-B2 | Pyrrole and pyrazole derivatives as potentiators of glutamate receptors | ELI LILLY AND COMPANY (US) | 2009-12-01 | — | — | US | disclosed |
| US-7625932-B2 | Pyrrole and pyrazole derivatives as potentiators of glutamate receptors | ELI LILLY AND COMPANY (US) | 2009-12-01 | — | — | US | disclosed |
| EP-1670757-B1 | PYRROLE AND PYRAZOLE DERIVATIVES AS POTENTIATORS OF GLUTAMATE RECEPTORS | LILLY CO ELI (US) | 2009-05-06 | — | — | EP | disclosed |
| US-5480576-A | SILVER ANTITARNISH | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1996-01-02 | — | — | US | disclosed |
| US-5468410-A | Antitarnish for silver | LEVER BROTHERS COMPANY | 1995-11-21 | — | — | US | disclosed |
| WO-1995010588-A1 | DETERGENT COMPOSITIONS CONTAINING SILVER ANTI-TARNISHING AGENTS | UNILEVER N.V. (NL) | 1995-04-20 | — | — | WO | disclosed |
| US-5374369-A | Mixture of a bleaching agent, (iso)cyanuric acid, builder and surfactant | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1994-12-20 | — | — | US | disclosed |
| EP-0461040-A1 | Imidazol derivatives, their process for production, intermediates, their application as medicaments and the pharmaceutical compositions containing them | ROUSSEL UCLAF (FR) | 1991-12-11 | — | — | EP | disclosed |
| EP-0059983-B1 | SUBSTITUTED BIPHENYL COMPOUNDS FOR USE AS A MEDICAMENT | THE WELLCOME FOUNDATION LIMITED (GB) | 1986-06-11 | — | — | EP | disclosed |
| US-4578522-A | CHEMICAL INTERMEDIATES FOR BLOOD LIPID CONTROLLING COMPOUNDS | BURROUGHS WELLCOME CO. | 1986-03-25 | — | — | US | disclosed |
| EP-0059983-A1 | Substituted biphenyl compounds for use as a medicament | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-09-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023741-A1 | ARYL/HETARYLAMIDES AS MODULATORS OF THE EP2 RECEPTOR | PTGER2, PTGER1, PTGDR2 | SLC6A3 4442/4885AKR1C3 535/4885HNF4A 853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.