Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.47 |
| ▸ | S100A4 | P26447 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23629159 | 0.88 | ALDH1A1 (0.56) | ALDH1A1HPGDTDP1GPR35S100A4 | |
| SCHEMBL21519475 | 0.88 | ALDH1A1 (0.56) | ALDH1A1HPGDTDP1GPR35S100A4 | |
| SCHEMBL4691140 | 0.88 | ALDH1A1 (0.56) | ALDH1A1HPGDTDP1GPR35S100A4 | |
| SCHEMBL31143078 | 0.84 | ALDH1A1 (0.56) | ALDH1A1HPGDTDP1SMN1; SMN2RECQL | |
| SCHEMBL942641 | 0.84 | ALDH1A1 (0.56) | ALDH1A1HPGDTDP1SMN1; SMN2RECQL | |
| SCHEMBL11356039 | 0.81 | ALDH1A1 (0.51) | ALDH1A1HPGDTDP1SMN1; SMN2RECQL | |
| SCHEMBL11362222 | 0.79 | NPC1 (0.49) | ALDH1A1HPGDTDP1SMN1; SMN2RECQL | |
| SCHEMBL18396554 | 0.79 | ALDH1A1 (0.54) | ALDH1A1HPGDTDP1TSHRSMN1; SMN2 | |
| SCHEMBL181041 | 0.78 | ALDH1A1 (1.00) | ALDH1A1HPGDTDP1TSHRSMN1; SMN2 | |
| SCHEMBL7291481 | 0.78 | ALDH1A1 (0.72) | ALDH1A1HPGDTDP1GPR35S100A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8710260-B2 | Process for preparing substituted aromatic carboxylic acids | PERKINELMER HEALTH SCIENCES, INC. (US) | 2014-04-29 | — | — | US | disclosed |
| US-20100228048-A1 | PROCESS FOR PREPARING SUBSTITUTED AROMATIC CARBOXYLIC ACIDS | PERKINELMER HEALTH SCIENCES, INC. (US) | 2010-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100228048-A1 | PROCESS FOR PREPARING SUBSTITUTED AROMATIC CARBOXYLIC ACIDS | PAH, HAO2, DDC | ALDH1A1 107/4885HPGD 217/4885TDP1 2466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.