Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6622422 | 0.80 | PRNP (0.41) | ALDH1A1PRNPRXFP1GPR3ALOX5 | |
| Hydrochloric Acid SCHEMBL5751827 | 0.79 | ALDH1A1 (0.38) | ALDH1A1PRNPRXFP1GPR3ALOX5 | |
| SCHEMBL5250330 | 0.78 | ROCK1 (0.43) | MAPTROCK1CYP2A6L3MBTL1KDM4E | |
| SCHEMBL12425595 | 0.74 | GPR3 (0.46) | ALDH1A1PRNPRXFP1GPR3ALOX5 | |
| SCHEMBL4093915 | 0.73 | GPR3 (0.44) | ALDH1A1PRNPRXFP1GPR3ALOX5 | |
| SCHEMBL22320228 | 0.72 | GPR3 (0.40) | ALDH1A1PRNPRXFP1GPR3ALOX5 | |
| SCHEMBL27599200 | 0.70 | PRNP (0.41) | ALDH1A1PRNPRXFP1ALOX5HSD11B1 | |
| SCHEMBL157274 | 0.69 | TUBB4A (0.48) | ALDH1A1PRNPRXFP1GPR3HSD11B1 | |
| SCHEMBL4099685 | 0.69 | GPR3 (0.40) | ALDH1A1PRNPRXFP1GPR3ALOX5 | |
| SCHEMBL4099681 | 0.69 | GPR3 (0.40) | ALDH1A1PRNPRXFP1GPR3ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2265606-A1 | HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2010-12-29 | — | — | EP | disclosed |
| WO-2009129109-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-10-22 | — | — | WO | disclosed |