Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL3419843 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Water SCHEMBL4395787 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Water SCHEMBL3417999 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Water SCHEMBL8530177 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Water SCHEMBL8531700 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| SCHEMBL31614995 | 0.98 | HIF1A (0.58) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| SCHEMBL31168138 | 0.98 | HIF1A (0.58) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Decyltriphenylphosphonium SCHEMBL29772910 | 0.98 | HIF1A (0.58) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Water SCHEMBL7695338 | 0.98 | HIF1A (0.58) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| SCHEMBL29375680 | 0.98 | HIF1A (0.58) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130161840-A1 | STRIPPER SOLUTIONS EFFECTIVE FOR BACK-END-OF-LINE OPERATIONS | DYNALOY LLC (US) | 2013-06-27 | — | — | US | claimed |
| US-8440389-B2 | Stripper solutions effective for back-end-of-line operations | DYNALOY, LLC (US) | 2013-05-14 | — | — | US | claimed |
| US-20100221503-A1 | STRIPPER SOLUTIONS EFFECTIVE FOR BACK-END-OF-LINE OPERATIONS | DYNALOY LLC (US) | 2010-09-02 | — | — | US | claimed |
| WO-2010008877-A1 | STRIPPER SOLUTIONS EFFECTIVE FOR BACK-END-OF LINE OPERATIONS | DYNALOY LLC (US) | 2010-01-21 | — | — | WO | claimed |
| US-12522632-B2 | Method for extracting keratin from wool/natural fibers using ionic liquids reinforced with sonication | Najran University (SA) | 2026-01-13 | — | — | US | disclosed |
| US-20240239837-A1 | METHOD FOR EXTRACTING KERATIN FROM WOOL/NATURAL FIBERS USING IONIC LIQUIDS REINFORCED WITH SONICATION | Najran University (SA) | 2024-07-18 | — | — | US | disclosed |
| WO-2024095923-A1 | CLEANING LIQUID AND METHOD FOR CLEANING SUBSTRATE | 東京応化工業株式会社 | 2024-05-10 | — | — | WO | disclosed |
| WO-2024095926-A1 | CLEANING LIQUID AND SUBSTRATE CLEANING METHOD | 東京応化工業株式会社 | 2024-05-10 | — | — | WO | disclosed |
| US-20240117280-A1 | METAL RESIDUE REMOVING LIQUID, METAL RESIDUE REMOVING METHOD, AND METAL WIRING MANUFACTURING METHOD | TOKYO OHKA KOGYO CO., LTD. (JP) | 2024-04-11 | — | — | US | disclosed |
| CN-117720972-A | Metal residue removing liquid, metal residue removing method, and metal wiring manufacturing method | 东京应化工业株式会社 | 2024-03-19 | — | — | CN | disclosed |
| US-20230203408-A1 | CLEANING LIQUID AND METHOD FOR CLEANING SUBSTRATE | TOKYO OHKA KOGYO CO., LTD. (JP) | 2023-06-29 | — | — | US | disclosed |
| US-20230203409-A1 | CLEANING LIQUID AND METHOD FOR CLEANING SUBSTRATE | TOKYO OHKA KOGYO CO., LTD. (JP) | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239837-A1 | METHOD FOR EXTRACTING KERATIN FROM WOOL/NATURAL FIBERS USING IONIC LIQUIDS REINFORCED WITH SONICATION | KRT18, CKAP4, ANKK1 | HIF1A 4183/4885TRAP1 2400/4885CHRNA7 2052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.