Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 9/20 | 0.44 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL8531700 | 0.98 | HIF1A (0.56) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Water SCHEMBL3417396 | 0.98 | HIF1A (0.56) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Water SCHEMBL3419843 | 0.98 | HIF1A (0.56) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Water SCHEMBL8530177 | 0.98 | HIF1A (0.56) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Water SCHEMBL4395787 | 0.98 | HIF1A (0.56) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Water SCHEMBL3417999 | 0.98 | HIF1A (0.56) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| SCHEMBL30620066 | 0.98 | HIF1A (0.61) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Iodide SCHEMBL5088274 | 0.96 | HIF1A (0.58) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Bromide SCHEMBL131195 | 0.96 | HIF1A (0.58) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| SCHEMBL31168138 | 0.96 | HIF1A (0.58) | HIF1AALDH1A1CYP1A2CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673959-B1 | Process for producing aromatic polycarbonate | MITSUBISHI CHEM CORP (JP) | 1998-10-28 | — | — | EP | claimed |
| US-5527875-A | Process for producing aromatic polycarbonate | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-06-18 | — | — | US | claimed |
| EP-0673959-A1 | Process for producing aromatic polycarbonate | Mitsubishi Chemical Corporation (JP) | 1995-09-27 | — | — | EP | claimed |
| US-12460019-B2 | Preparation of regenerated polysaccharides | UNIVERSITAET ROSTOCK (DE) | 2025-11-04 | — | — | US | disclosed |
| CN-115175943-B | Preparation of regenerated polysaccharide | 罗斯托克大学 | 2024-12-17 | — | — | CN | disclosed |
| US-20230050320-A1 | PREPARATION OF REGENERATED POLYSACCHARIDES | UNIVERSITAET ROSTOCK (DE) | 2023-02-16 | — | — | US | disclosed |
| CN-115175943-A | Preparation of regenerated polysaccharides | 罗斯托克大学 | 2022-10-11 | — | — | CN | disclosed |
| EP-3990501-A1 | PREPARATION OF REGENERATED POLYSACCHARIDES | Universität Rostock (DE) | 2022-05-04 | — | — | EP | disclosed |
| WO-2021130323-A1 | PREPARATION OF REGENERATED POLYSACCHARIDES | UNIVERSITÄT ROSTOCK (DE) | 2021-07-01 | — | — | WO | disclosed |
| WO-2020203345-A1 | COATING STRIPPING AGENT AND COATING STRIPPING METHOD | 王子ホールディングス株式会社 | 2020-10-08 | — | — | WO | disclosed |
| US-9217043-B2 | Process for producing solid cellulose and process for producing cellulose ester | DAICEL CORPORATION (JP) | 2015-12-22 | — | — | US | disclosed |
| US-20140212670-A1 | PROCESS FOR PRODUCING SOLID CELLULOSE AND PROCESS FOR PRODUCING CELLULOSE ESTER | DAICEL CORPORATION (JP) | 2014-07-31 | — | — | US | disclosed |
| US-20110311426-A1 | PROCESS FOR THE PREPARATION OF FLUORINE COMPOUND | STELLA CHEMIFA CORPORATION (JP) | 2011-12-22 | — | — | US | disclosed |
| EP-2397438-A1 | PROCESS FOR THE PREPARATION OF FLUORINE COMPOUND | Stella Chemifa Corporation (JP) | 2011-12-21 | — | — | EP | disclosed |
| US-6476249-B1 | Copolycarbonate and process for producing the same | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2002-11-05 | — | — | US | disclosed |
| WO-1999019397-A1 | STABILIZED POLYOLEFIN | DSM N.V. (NL) | 1999-04-22 | — | — | WO | disclosed |
| EP-0673959-B1 | Process for producing aromatic polycarbonate | MITSUBISHI CHEM CORP (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5527875-A | Process for producing aromatic polycarbonate | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-06-18 | — | — | US | disclosed |
| EP-0673959-A1 | Process for producing aromatic polycarbonate | Mitsubishi Chemical Corporation (JP) | 1995-09-27 | — | — | EP | disclosed |