Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11300513 | 0.86 | ALDH1A1 (0.39) | CYP2C19TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4154409 | 0.85 | TSHR (0.39) | CYP2C19TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11488213 | 0.85 | CYP1A2 (0.36) | CYP2C19TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8360217 | 0.83 | CA2 (0.40) | TSHRCYP3A4MAPK1RXRAALDH1A1 | |
| SCHEMBL31556870 | 0.81 | APEX1 (0.39) | CYP2C19TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7115234 | 0.81 | APEX1 (0.39) | CYP2C19TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL17807568 | 0.79 | CYP3A4 (0.37) | CYP2C19TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7644132 | 0.79 | CYP1A2 (0.33) | CYP2C19TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8634811 | 0.78 | ALDH1A1 (0.36) | TSHRCYP1A2CYP3A4TNFRSF1ATACR1 | |
| SCHEMBL11525106 | 0.78 | CYP1A2 (0.37) | CYP2C19TSHRCYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0004026-B1 | HYDROLYTICALLY STABLE ORTHO-ALKYLATED PHENYL PHOSPHONITES AND STABILIZED COMPOSITIONS | CIBA-GEIGY AG (CH) | 1982-05-05 | — | — | EP | claimed |
| US-20100252786-A1 | CELLULOSE ESTER FILM, METHOD OF MANUFACTURING THE SAME, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY | KONICA MINOLTA OPTO, INC. (JP) | 2010-10-07 | — | — | US | disclosed |
| US-20100103352-A1 | OPTICAL FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY AND ULTRAVIOLET ABSORBING POLYMER | KONICA MINOLTA OPTO, INC. (JP) | 2010-04-29 | — | — | US | disclosed |