Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 2/20 | 0.38 |
| ▸ | CD44 | P16070 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13075535 | 1.00 | ADRB2 (0.52) | ADRB2S1PR1LMNATP53HTT | |
| SCHEMBL8185537 | 1.00 | ADRB2 (0.52) | ADRB2S1PR1LMNATP53HTT | |
| Hydrochloric Acid SCHEMBL3715367 | 0.98 | ADRB2 (0.50) | ADRB2S1PR1LMNATP53HTT | |
| SCHEMBL2273892 | 0.83 | S1PR1 (0.43) | ADRB2S1PR1LMNATP53HTT | |
| SCHEMBL8286723 | 0.83 | ADRB2 (0.52) | ADRB2LMNATP53HTTPNMT | |
| SCHEMBL29453111 | 0.82 | ADRB2 (0.56) | ADRB2LMNATP53HTTPNMT | |
| SCHEMBL1104688 | 0.82 | LMNA (0.52) | S1PR1LMNAHTTAKR1C3AKR1C2 | |
| SCHEMBL5862322 | 0.82 | ADRB2 (0.56) | ADRB2LMNATP53HTTPNMT | |
| SCHEMBL61975 | 0.82 | ADRB2 (0.56) | ADRB2LMNATP53HTTPNMT | |
| SCHEMBL3181409 | 0.82 | ADRB2 (0.56) | ADRB2LMNATP53HTTPNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848494-B | Guanidine compounds and uses thereof | 伊谬诺米特医疗有限公司 | 2023-08-01 | — | — | CN | disclosed |
| US-10844044-B2 | WDR5 inhibitors and modulators | VANDERBILT UNIVERSITY (US) | 2020-11-24 | — | — | US | disclosed |
| WO-2020221380-A1 | SELECTIVE LIGANDS OF HUMAN CONSTITUTIVE ANDROSTANE RECEPTOR | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V. V. I. (CZ) | 2020-11-05 | — | — | WO | disclosed |
| CN-111848494-A | Guanidine compounds and uses thereof | 伊谬诺米特医疗有限公司 | 2020-10-30 | — | — | CN | disclosed |
| US-10807959-B2 | WDR5-MLL1 inhibitors and modulators | VANDERBILT UNIVERSITY (US) | 2020-10-20 | — | — | US | disclosed |
| US-20200102288-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2020-04-02 | — | — | US | disclosed |
| US-20200055824-A1 | WDR5-MLL1 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2020-02-20 | — | — | US | disclosed |
| US-9365491-B2 | Inhibitors of cognitive decline | COGNITION THERAPEUTICS, INC. (US) | 2016-06-14 | — | — | US | disclosed |
| US-8921405-B2 | Compounds | OREXO AB (SE) | 2014-12-30 | — | — | US | disclosed |
| US-20140371324-A1 | INHIBITORS OF COGNITIVE DECLINE | COGNITION THERAPEUTICS, INC. (US) | 2014-12-18 | — | — | US | disclosed |
| US-20120095105-A1 | INHIBITORS OF COGNITIVE DECLINE | COGNITION THERAPEUTICS, INC. (US) | 2012-04-19 | — | — | US | disclosed |
| EP-1222178-A1 | ALKYL-AMINO-1,3,5-TRIAZINES AND THEIR USE AS HERBICIDES | Aventis CropScience GmbH (DE) | 2002-07-17 | — | — | EP | disclosed |
| WO-2001027093-A1 | ALKYL-AMINO-1,3,5-TRIAZINES AND THEIR USE AS HERBICIDES | AVENTIS CROPSCIENCE GMBH (DE) | 2001-04-19 | — | — | WO | disclosed |
| US-6093851-A | N-(α-alkylbenzylidene)-α-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2000-07-25 | — | — | US | disclosed |
| EP-0735018-B1 | N-(alpha-alkylbenzylidene)-alpha-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor | SUMITOMO CHEMICAL CO (JP) | 1999-07-21 | — | — | EP | disclosed |
| US-5739401-A | N-(α-alkylbenzylidene)-α-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-04-14 | — | — | US | disclosed |
| EP-0735018-A1 | N-(alpha-alkylbenzylidene)-alpha-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |
| EP-0191496-B1 | TRIAZINE DERIVATIVES, A PROCESS FOR PREPARING THE DERIVATIVES, AND HERBICIDES CONTAINING THE DERIVATIVES AS THE EFFECTIVE COMPONENT | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1990-10-31 | — | — | EP | disclosed |
| US-4680054-A | Triazine derivatives, a process for preparing the derivatives, and herbicides containing the derivatives as the effective component | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1987-07-14 | — | — | US | disclosed |
| EP-0191496-A2 | Triazine Derivatives, a process for preparing the derivatives, and herbicides containing the derivatives as the effective component | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1986-08-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200102288-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | ADRB2 4754/4885S1PR1 3779/4885LMNA 2317/4885 |
| US-20120095105-A1 | INHIBITORS OF COGNITIVE DECLINE | PSEN2, ACHE, MAPT | ADRB2 508/4885S1PR1 1411/4885LMNA 3447/4885 |
| US-20140371324-A1 | INHIBITORS OF COGNITIVE DECLINE | PSEN2, ACHE, MAPT | ADRB2 508/4885S1PR1 1411/4885LMNA 3447/4885 |
| US-10844044-B2 | WDR5 inhibitors and modulators | WDR5, WDR1, WDR3 | ADRB2 4707/4885S1PR1 3691/4885LMNA 2328/4885 |
| US-10807959-B2 | WDR5-MLL1 inhibitors and modulators | WDR5, WDR1, WDR3 | ADRB2 4745/4885S1PR1 2610/4885LMNA 2165/4885 |
| US-20200055824-A1 | WDR5-MLL1 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | ADRB2 4745/4885S1PR1 2610/4885LMNA 2165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.