Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.90 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.90 |
| ▸ | EGFR | P00533 | 2/20 | 0.90 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.90 |
| ▸ | LMNA | P02545 | 1/20 | 0.90 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | RAF1 | P04049 | 1/20 | 0.65 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.65 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | NSD2 | O96028 | 2/20 | 0.54 |
| ▸ | DRD3 | P35462 | 5/20 | 0.50 |
| ▸ | DRD2 | P14416 | 4/20 | 0.50 |
| ▸ | HTR6 | P50406 | 3/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3419792 | 0.80 | MAPT (0.60) | MAPTKMT2AEGFRMAPK1LMNA | |
| SCHEMBL7060111 | 0.79 | MAPT (0.65) | MAPTKMT2AEGFRMAPK1LMNA | |
| SCHEMBL2463193 | 0.79 | MAPT (1.00) | MAPTKMT2AEGFRMAPK1LMNA | |
| SCHEMBL3273424 | 0.77 | MAPT (0.97) | MAPTKMT2AEGFRMAPK1LMNA | |
| SCHEMBL6661677 | 0.76 | MAPT (1.00) | MAPTKMT2AEGFRMAPK1LMNA | |
| SCHEMBL7063665 | 0.75 | MAPT (0.73) | MAPTKMT2AEGFRMAPK1LMNA | |
| SCHEMBL14983914 | 0.75 | MAPT (1.00) | MAPTKMT2AEGFRMAPK1LMNA | |
| SCHEMBL30775366 | 0.73 | EGFR (0.54) | MAPTKMT2AEGFRMAPK1LMNA | |
| SCHEMBL8231662 | 0.72 | LMNA (0.52) | MAPTKMT2AEGFRMAPK1LMNA | |
| SCHEMBL10522546 | 0.72 | KMT2A (0.52) | MAPTKMT2AEGFRMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9334281-B2 | Fluorochromes for organelle tracing and multi-color imaging | ENZO LIFE SCIENCES, INC. (US) | 2016-05-10 | — | — | US | disclosed |
| US-9334281-B2 | Fluorochromes for organelle tracing and multi-color imaging | ENZO LIFE SCIENCES, INC. (US) | 2016-05-10 | — | — | US | disclosed |
| US-9334281-B2 | Fluorochromes for organelle tracing and multi-color imaging | ENZO LIFE SCIENCES, INC. (US) | 2016-05-10 | — | — | US | disclosed |
| US-8715944-B2 | Fluorochromes for organelle tracing and multi-color imaging | ENZO LIFE SCIENCES, INC. (US) | 2014-05-06 | — | — | US | disclosed |
| US-8715944-B2 | Fluorochromes for organelle tracing and multi-color imaging | ENZO LIFE SCIENCES, INC. (US) | 2014-05-06 | — | — | US | disclosed |
| US-8715944-B2 | Fluorochromes for organelle tracing and multi-color imaging | ENZO LIFE SCIENCES, INC. (US) | 2014-05-06 | — | — | US | disclosed |
| US-20100062429-A1 | Fluorochromes for organelle tracing and multi-color imaging | ENZO LIFE SCIENCES, INC. | 2010-03-11 | — | — | US | disclosed |
| WO-2010028349-A2 | FLUOROCHROMES FOR ORGANELLE TRACING AND MULTI-COLOR IMAGING | ENZO LIFE SCIENCES, INC. (US) | 2010-03-11 | — | — | WO | disclosed |
| US-20100062429-A1 | Fluorochromes for organelle tracing and multi-color imaging | ENZO LIFE SCIENCES, INC. | 2010-03-11 | — | — | US | disclosed |
| US-20100062429-A1 | Fluorochromes for organelle tracing and multi-color imaging | ENZO LIFE SCIENCES, INC. | 2010-03-11 | — | — | US | disclosed |
| US-20100062460-A1 | Novel fluorochromes for organelle tracing and multi-color imaging | ENZO LIFE SCIENCES, INC. | 2010-03-11 | — | — | US | disclosed |
| US-20100062460-A1 | Novel fluorochromes for organelle tracing and multi-color imaging | ENZO LIFE SCIENCES, INC. | 2010-03-11 | — | — | US | disclosed |
| US-20100062460-A1 | Novel fluorochromes for organelle tracing and multi-color imaging | ENZO LIFE SCIENCES, INC. | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100062429-A1 | Fluorochromes for organelle tracing and multi-color imaging | MFN2, TFEB, NDC1 | MAPT 469/4885KMT2A 2915/4885EGFR 4732/4885 |
| US-20100062460-A1 | Novel fluorochromes for organelle tracing and multi-color imaging | MFN2, TFEB, NUMA1 | MAPT 574/4885KMT2A 3046/4885EGFR 4790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.