SCHEMBL3419792

SCHEMBL3419792

CN(C)CCNc1cccc2c1C(=O)c1cccc(N3CCN(C)CC3)c1C2=O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.60
EGFR P00533 3/20 0.60
MAPK1 P28482 3/20 0.60
KMT2A Q03164 3/20 0.60
LMNA P02545 2/20 0.60
EHMT2 Q96KQ7 7/20 0.56
NPSR1 Q6W5P4 3/20 0.46
TERT O14746 3/20 0.45
TOP2A P11388 1/20 0.44
L3MBTL1 Q9Y468 4/20 0.44
ALDH1A1 P00352 2/20 0.44
RAF1 P04049 1/20 0.44
ALOX12 P18054 1/20 0.44
MAP2K1 Q02750 1/20 0.44
TDP1 Q9NUW8 2/20 0.43
MEN1 O00255 2/20 0.42
POLB P06746 1/20 0.42
HTT P42858 1/20 0.42
RAD52 P43351 1/20 0.42
RECQL P46063 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13434518 0.89 MAPT (0.52) MAPTEGFRMAPK1KMT2ALMNA
SCHEMBL3418821 0.83 TERT (0.61) MAPTEGFRMAPK1KMT2ALMNA
SCHEMBL13434540 0.81 TERT (0.57) MAPTEGFRMAPK1KMT2ALMNA
SCHEMBL3418386 0.80 MAPT (0.90) MAPTEGFRMAPK1KMT2ALMNA
SCHEMBL3418752 0.79 MAPT (0.63) MAPTEGFRMAPK1KMT2ALMNA
SCHEMBL31218585 0.79 MAPT (0.63) MAPTEGFRMAPK1KMT2ALMNA
SCHEMBL3416154 0.79 TERT (0.62) MAPTEGFRMAPK1KMT2ALMNA
SCHEMBL13434544 0.78 SMN1; SMN2 (0.59) MAPTEGFRMAPK1KMT2ALMNA
SCHEMBL14882640 0.78 TERT (0.56) MAPTEGFRMAPK1KMT2ALMNA
SCHEMBL3415549 0.76 NSD2 (0.62) MAPTEGFRMAPK1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9334281-B2 Fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. (US) 2016-05-10 US disclosed
US-9334281-B2 Fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. (US) 2016-05-10 US disclosed
US-9334281-B2 Fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. (US) 2016-05-10 US disclosed
US-8715944-B2 Fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. (US) 2014-05-06 US disclosed
US-8715944-B2 Fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. (US) 2014-05-06 US disclosed
US-8715944-B2 Fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. (US) 2014-05-06 US disclosed
US-20100062429-A1 Fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. 2010-03-11 US disclosed
US-20100062429-A1 Fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. 2010-03-11 US disclosed
US-20100062429-A1 Fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. 2010-03-11 US disclosed
WO-2010028349-A2 FLUOROCHROMES FOR ORGANELLE TRACING AND MULTI-COLOR IMAGING ENZO LIFE SCIENCES, INC. (US) 2010-03-11 WO disclosed
WO-2010028349-A2 FLUOROCHROMES FOR ORGANELLE TRACING AND MULTI-COLOR IMAGING ENZO LIFE SCIENCES, INC. (US) 2010-03-11 WO disclosed
US-20100062460-A1 Novel fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. 2010-03-11 US disclosed
US-20100062460-A1 Novel fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. 2010-03-11 US disclosed
US-20100062460-A1 Novel fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. 2010-03-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100062429-A1 Fluorochromes for organelle tracing and multi-color imaging MFN2, TFEB, NDC1 MAPT 469/4885EGFR 4732/4885MAPK1 2481/4885
US-20100062460-A1 Novel fluorochromes for organelle tracing and multi-color imaging MFN2, TFEB, NUMA1 MAPT 574/4885EGFR 4790/4885MAPK1 2174/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.