SCHEMBL3418528

SCHEMBL3418528

S=C1SCCN1c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.47
KMT2A Q03164 3/20 0.47
ALDH1A1 P00352 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2C19 P33261 1/20 0.47
SIGMAR1 Q99720 3/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
MEN1 O00255 1/20 0.43
GAA P10253 2/20 0.40
KDM4E B2RXH2 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
LMNA P02545 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
ATM Q13315 2/20 0.38
CNR1 P21554 1/20 0.38
NPSR1 Q6W5P4 1/20 0.37
DDB1 Q16531 1/20 0.36
CRBN Q96SW2 1/20 0.36
MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11553723 0.81 MAPT (0.44) MAPTKMT2AALDH1A1CYP1A2CYP2C19
SCHEMBL10386947 0.75 SIGMAR1 (0.54) MAPTKMT2AALDH1A1SIGMAR1NPC1
SCHEMBL6360683 0.75 MEN1 (0.54) MAPTKMT2AALDH1A1SIGMAR1NPC1
Bromide SCHEMBL10800477 0.73 SIGMAR1 (0.52) MAPTKMT2AALDH1A1SIGMAR1NPC1
SCHEMBL11188803 0.73 DDB1 (0.42) MAPTKMT2AALDH1A1CYP1A2CYP2C19
SCHEMBL28566678 0.72 MAPT (0.58) MAPTKMT2AALDH1A1CYP1A2CYP2C19
SCHEMBL3257577 0.70 SIGMAR1 (0.58) MAPTKMT2ASIGMAR1NPC1RAB9A
SCHEMBL13917942 0.67 ATM (0.49) MAPTKMT2ASIGMAR1NPC1RAB9A
SCHEMBL10416940 0.67 KMT2A (0.58) MAPTKMT2AALDH1A1CYP1A2CYP2C19
SCHEMBL23769116 0.66 MAPT (0.42) MAPTKMT2AALDH1A1CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114514936-A Application of thiazole thione in preparing bird repellent 宁波三江益农化学有限公司 2022-05-20 CN claimed
EP-3826982-B1 USE OF A SUBSTITUTED THIAZOLIDINE COMPOUND AS NITRIFICATION INHIBITOR BASF SE (DE) 2023-11-01 EP disclosed
CN-114514936-B Application of thiazole thioketone in preparation of bird repellent 宁波三江益农化学有限公司 2023-08-18 CN disclosed
CN-112955503-B Chloroprene rubber composition and vulcanized molded article 电化株式会社 2022-10-21 CN disclosed
CN-114514936-A Application of thiazole thione in preparing bird repellent 宁波三江益农化学有限公司 2022-05-20 CN disclosed
CN-114514936-A Application of thiazole thione in preparing bird repellent 宁波三江益农化学有限公司 2022-05-20 CN disclosed
EP-3862389-B1 CHLOROPRENE RUBBER COMPOSITION AND VULCANIZATION MOLDED BODY DENKA COMPANY LTD (JP) 2022-02-23 EP disclosed
US-20220002526-A1 CHLOROPRENE RUBBER COMPOSITION AND VULCANIZATION MOLDED BODY DENKA COMPANY LIMITED (JP) 2022-01-06 US disclosed
US-20210276930-A1 USE OF A SUBSTITUTED THIAZOLIDINE COMPOUND AS NITRIFICATION INHIBITOR BASF SE (DE) 2021-09-09 US disclosed
EP-3862389-A1 CHLOROPRENE RUBBER COMPOSITION AND VULCANIZATION MOLDED BODY Denka Company Limited (JP) 2021-08-11 EP disclosed
EP-1954652-A2 AN IMPROVED PROCESS FOR THE PREPARATION OF ARMODAFINIL Teva Pharmaceutical Industries Ltd (IL) 2008-08-13 EP disclosed
WO-2008039829-A2 DIPHENYLHETEROCYCLE CHOLESTEROL ABSORPTION INHIBITORS IRONWOOD PHARMACEUTICALS, INC. (US) 2008-04-03 WO disclosed
US-20080031939-A1 Process for the preparation of armodafinil TEVA PHARMACEUTICALS USA, INC. 2008-02-07 US disclosed
WO-2007103221-A2 AN IMPROVED PROCESS FOR THE PREPARATION OF ARMODAFINIL TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 2007-09-13 WO disclosed
WO-2006102674-A2 DIPHENYLHETEROCYCLE CHOLESTEROL ABSORPTION INHIBITORS MICROBIA, INC. (US) 2006-09-28 WO disclosed
EP-0988295-A4 HETEROCYCLIC SUBSTITUTED PIPERIDINES AND USES THEREOF SYNAPTIC PHARMA CORP (US) 2003-08-13 EP disclosed
EP-0988295-A1 HETEROCYCLIC SUBSTITUTED PIPERIDINES AND USES THEREOF SYNAPTIC PHARMACEUTICAL CORPORATION (US) 2000-03-29 EP disclosed
WO-1998057940-A1 HETEROCYCLIC SUBSTITUTED PIPERIDINES AND USES THEREOF SYNAPTIC PHARMACEUTICAL CORPORATION (US) 1998-12-23 WO disclosed
EP-0017039-B1 PROCESS FOR THE PREPARATION OF THIAZOLIDINE-2-THIONES BAYER AG (DE) 1983-01-12 EP disclosed
EP-0017039-A1 Process for the preparation of thiazolidine-2-thiones BAYER AG (DE) 1980-10-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080031939-A1 Process for the preparation of armodafinil CYP2F1, CYP4F11, CYP4F2 MAPT 2192/4885KMT2A 2108/4885ALDH1A1 344/4885
US-20210276930-A1 USE OF A SUBSTITUTED THIAZOLIDINE COMPOUND AS NITRIFICATION INHIBITOR NAT1, NOS1, NOS2 MAPT 2278/4885KMT2A 2909/4885ALDH1A1 332/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.