Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | GSK3A | P49840 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1520285 | 0.89 | KMT2A (0.55) | KMT2AMEN1LMNAHTTALDH1A1 | |
| SCHEMBL10440873 | 0.84 | ALDH1A1 (0.56) | KMT2AMEN1LMNAHTTALDH1A1 | |
| SCHEMBL10441288 | 0.82 | TAAR1 (0.60) | KMT2AMEN1LMNAHTTALDH1A1 | |
| SCHEMBL13946686 | 0.82 | HTT (0.52) | KMT2AMEN1LMNAHTTALDH1A1 | |
| SCHEMBL25002012 | 0.78 | CHRNA1 (0.60) | KMT2AMEN1LMNAHTTALDH1A1 | |
| SCHEMBL4182979 | 0.78 | MAPK1 (0.57) | KMT2AMEN1LMNAALDH1A1CYP2C19 | |
| SCHEMBL10617833 | 0.77 | CHRNA7 (0.40) | KMT2AMEN1LMNAHTTALDH1A1 | |
| Bromide SCHEMBL9512786 | 0.76 | CHRNA1 (0.59) | KMT2AMEN1LMNAHTTALDH1A1 | |
| SCHEMBL10613844 | 0.76 | CHRNA7 (0.70) | KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6744475 | 0.74 | SIGMAR1 (0.54) | KMT2AMEN1LMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114514936-A | Application of thiazole thione in preparing bird repellent | 宁波三江益农化学有限公司 | 2022-05-20 | — | — | CN | claimed |
| CN-114514936-B | Application of thiazole thioketone in preparation of bird repellent | 宁波三江益农化学有限公司 | 2023-08-18 | — | — | CN | disclosed |
| CN-114514936-A | Application of thiazole thione in preparing bird repellent | 宁波三江益农化学有限公司 | 2022-05-20 | — | — | CN | disclosed |
| CN-114514936-A | Application of thiazole thione in preparing bird repellent | 宁波三江益农化学有限公司 | 2022-05-20 | — | — | CN | disclosed |
| CN-110156874-A | Cyclodepsipeptide compound | 恩库勒公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-106456613-B | Process for preparing cyclodepsipeptides | 恩库勒公司 | 2019-07-09 | — | — | CN | disclosed |
| US-9649292-B2 | Method for treating prostate cancer and/or gastrointestinal cancer | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2017-05-16 | — | — | US | disclosed |
| US-20170100365-A1 | METHOD FOR TREATING PROSTATE CANCER AND/OR GASTROINTESTINAL CANCER | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2017-04-13 | — | — | US | disclosed |
| US-9487542-B1 | Mixed ligand gold(III) complexes and methods thereof | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2016-11-08 | — | — | US | disclosed |
| US-4937252-A | 2-thiazolidinone derivatives, pharmaceutical compositions containing them and process for preparing same | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1990-06-26 | — | — | US | disclosed |
| EP-0371733-A2 | Dopamine-beta-hydroxylase inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 1990-06-06 | — | — | EP | disclosed |
| EP-0320910-A1 | 2-Thiazolidinone derivatives, pharmaceutical compositions containing them, process for preparing same, and use | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1989-06-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170100365-A1 | METHOD FOR TREATING PROSTATE CANCER AND/OR GASTROINTESTINAL CANCER | CASP3, BAD, KLK3 | KMT2A 3811/4885MEN1 921/4885LMNA 1316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.