Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 15/20 | 0.47 |
| ▸ | DDO | Q99489 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3361624 | 0.79 | DAO (0.58) | DAODDO | |
| SCHEMBL3418623 | 0.76 | DAO (0.64) | DAODDOKMT2AKDM4EALDH1A1 | |
| SCHEMBL3421507 | 0.76 | DAO (0.58) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL31118648 | 0.74 | F11 (0.46) | KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL4707291 | 0.73 | GRIN1 (0.59) | KMT2AKDM4EGRIN2DGRIN3BALDH1A1 | |
| SCHEMBL3395947 | 0.72 | DAO (0.47) | DAODDO | |
| SCHEMBL3423488 | 0.71 | DAO (0.49) | DAODDOKMT2A | |
| SCHEMBL9365102 | 0.71 | DAO (0.36) | DAOKMT2AKDM4EGRIN2DGRIN3B | |
| SCHEMBL3419432 | 0.70 | DAO (0.51) | DAODDOKMT2AKDM4EALDH1A1 | |
| SCHEMBL3432869 | 0.69 | DAO (0.58) | DAODDO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |