Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 11/20 | 0.51 |
| ▸ | DDO | Q99489 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MPL | P40238 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3362656 | 0.83 | DAO (0.61) | DAODDOPGR | |
| SCHEMBL3423488 | 0.78 | DAO (0.49) | DAODDOMEN1LMNAHTT | |
| SCHEMBL3360150 | 0.77 | DAO (0.59) | DAODDOMEN1ALDH1A1HTT | |
| SCHEMBL3418623 | 0.74 | DAO (0.64) | DAODDOKDM4EMEN1ALDH1A1 | |
| SCHEMBL3432869 | 0.73 | DAO (0.58) | DAODDO | |
| SCHEMBL3424908 | 0.72 | DAO (0.53) | DAODDOKDM4EALDH1A1HPGD | |
| SCHEMBL3360159 | 0.72 | DAO (0.58) | DAODDOKDM4EALDH1A1PGR | |
| SCHEMBL3359175 | 0.71 | DAO (0.64) | DAODDOKDM4EMEN1ALDH1A1 | |
| SCHEMBL3431869 | 0.71 | DAO (0.49) | DAODDOMCL1PGRAR | |
| SCHEMBL3421760 | 0.70 | DAO (0.55) | DAODDOPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |