SCHEMBL3418657

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20100408	0.86	NPC1 (0.50)	CES2CES1NPC1RAB9ACRHBP
	SCHEMBL26163219	0.85	CES2 (0.57)	CES2CES1NPC1RAB9ACRHBP
	SCHEMBL3655196	0.80	CES2 (0.61)	CES2CES1NPC1RAB9ACRHBP
	SCHEMBL6991977	0.79	CES2 (0.59)	CES2CES1NPC1RAB9ACRHBP
	SCHEMBL25142228	0.77	CES2 (0.57)	CES2CES1NPC1RAB9ACRHBP
	SCHEMBL15328058	0.77	PTGS1 (0.59)	CES2CES1NPC1RAB9ACRHBP
	SCHEMBL1435351	0.76	CES2 (0.75)	CES2CES1TRPV1NR4A1NR4A2
	SCHEMBL72091	0.76	CES2 (0.67)	CES2CES1TRPV1NR4A1NR4A2
	SCHEMBL5428269	0.76	HDAC6 (0.56)	CES2CES1NPC1RAB9ACRHBP
	SCHEMBL3415035	0.76	EPHX2 (0.66)	NPC1RAB9ATRPV1PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.