Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1958128 | 0.89 | BCL2 (0.38) | BCL2 | |
| SCHEMBL2507853 | 0.88 | ALDH3A1 (0.42) | — | |
| SCHEMBL1954915 | 0.84 | BCL2 (0.43) | BCL2 | |
| SCHEMBL3419070 | 0.82 | BCL2 (0.55) | BCL2 | |
| SCHEMBL2506487 | 0.80 | BCL2 (0.42) | BCL2 | |
| SCHEMBL1959692 | 0.79 | L3MBTL1 (0.39) | BCL2 | |
| SCHEMBL3398580 | 0.77 | ALDH3A1 (0.39) | BCL2 | |
| SCHEMBL2484548 | 0.77 | BCL2 (0.54) | BCL2 | |
| SCHEMBL30112788 | 0.76 | BCL2L1 (0.55) | BCL2 | |
| SCHEMBL1743461 | 0.76 | TDP1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2507229-A1 | SULFONAMIDE DERIVATIVES AS BCL-2-SELECTIVE APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE DISEASES | Abbott Laboratories (US) | 2012-10-10 | — | — | EP | disclosed |
| WO-2010065865-A2 | BCL-2-SELECTIVE APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE DISEASES | ABBOTT LABORATORIES (US) | 2010-06-10 | — | — | WO | disclosed |