Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 11/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3398579 | 0.79 | BCL2 (0.53) | BCL2BCL2L1 | |
| SCHEMBL1958128 | 0.79 | BCL2 (0.38) | BCL2HCAR3 | |
| SCHEMBL3419072 | 0.77 | BCL2 (0.42) | BCL2 | |
| SCHEMBL2478518 | 0.77 | BCL2L1 (0.53) | ALDH3A1BCL2MEN1KMT2ABCL2L1 | |
| SCHEMBL1958806 | 0.76 | ALDH3A1 (0.45) | ALDH3A1BCL2HCAR3 | |
| SCHEMBL1699924 | 0.74 | WNK1 (0.51) | ALDH3A1MEN1KMT2AHCAR3POLB | |
| SCHEMBL30112788 | 0.73 | BCL2L1 (0.55) | ALDH3A1BCL2MEN1KMT2ABCL2L1 | |
| SCHEMBL19204112 | 0.72 | WNK1 (0.51) | ALDH3A1MEN1KMT2AHCAR3LMNA | |
| SCHEMBL2480796 | 0.72 | BCL2 (0.45) | ALDH3A1BCL2 | |
| SCHEMBL1700167 | 0.71 | WNK1 (0.47) | KMT2APOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010065865-A2 | BCL-2-SELECTIVE APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE DISEASES | ABBOTT LABORATORIES (US) | 2010-06-10 | — | — | WO | disclosed |