Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.56 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.60 |
| ▸ | THRB | P10828 | 2/20 | 0.60 |
| ▸ | BLM | P54132 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.60 |
| ▸ | GABRP | O00591 | 1/20 | 0.60 |
| ▸ | GABRD | O14764 | 1/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.60 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.60 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.60 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.60 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.60 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL3977001 | 0.94 | NFKB1 (0.54) | LMNATSHRKMT2AHDAC11THRB | |
| Ethylenediamine SCHEMBL11359615 | 0.83 | KDM4E (0.46) | LMNATSHRKMT2AHDAC11THRB | |
| SCHEMBL6534712 | 0.82 | KDM4E (0.50) | LMNATSHRKMT2AHDAC11THRB | |
| Ethylenediamine SCHEMBL11272751 | 0.79 | KDM4E (0.43) | LMNATSHRKMT2AHDAC11THRB | |
| Gamma-Aminobutyric Acid SCHEMBL4878 | 0.78 | — | — | |
| Gamma-Aminobutyric Acid SCHEMBL190459 | 0.78 | LMNA (1.00) | LMNATSHRKMT2AHDAC11THRB | |
| Gamma-Aminobutyric Acid SCHEMBL3973563 | 0.78 | LMNA (1.00) | LMNATSHRKMT2AHDAC11THRB | |
| Gamma-Aminobutyric Acid SCHEMBL1330421 | 0.78 | — | — | |
| SCHEMBL7118246 | 0.77 | CYP2D6 (0.52) | LMNATSHRKMT2AHDAC11THRB | |
| Gamma-Aminobutyric Acid SCHEMBL4357842 | 0.76 | TSHR (0.75) | LMNATSHRKMT2AHDAC11THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113980581-B | Environment-friendly suspending agent based on sapphire grinding, and preparation method and application thereof | 浙江奥首材料科技有限公司 | 2022-06-14 | — | — | CN | claimed |
| US-6455025-B1 | POLYSACCHARIDE-SOMATOSTATIN ANALOGS; SOMATOSTATIN IS DIRECTLY OR INDIRECTLY COUPLED FROM A TERMINAL N-AMINO GROUP OF THE SOMATOSTATIN ANALOG TO A POLYSACCHARIDE; EFFECTIVE NEGATIVE CHARGE; DIAGNOSING AND TREATING CANCERS; RADIOLABELED | MAP MEDICAL TECHNOLOGIES OY (FI) | 2002-09-24 | — | — | US | claimed |
| EP-1094783-A1 | DEPILATORY COMPOSITIONS COMPRISING CHELATING AGENTS | Miller, Matthew (AU) | 2001-05-02 | — | — | EP | claimed |
| EP-1005651-A1 | METHODS OF IDENTIFYING BIOLOGICAL AGENT COMPOSITIONS | SUPRATEK PHARMA, INC. (CA) | 2000-06-07 | — | — | EP | claimed |
| WO-1999053892-A1 | DEPILATORY COMPOSITIONS COMPRISING CHELATING AGENTS | MILLER MATTHEW (AU) | 1999-10-28 | — | — | WO | claimed |
| EP-0951478-A1 | POLYSACCHARIDE-PEPTIDE DERIVATIVES | Map Medical Technologies Oy (FI) | 1999-10-27 | — | — | EP | claimed |
| WO-1999008112-A1 | METHODS OF IDENTIFYING BIOLOGICAL AGENT COMPOSITIONS | SUPRATEK PHARMA INC. (CA) | 1999-02-18 | — | — | WO | claimed |
| WO-1998028336-A1 | POLYSACCHARIDE-PEPTIDE DERIVATIVES | MAP MEDICAL TECHNOLOGIES OY (FI) | 1998-07-02 | — | — | WO | claimed |
| US-11883472-B2 | Rusalatide acetate compositions | AFFIRMED PHARMA, LLC (US) | 2024-01-30 | — | — | US | disclosed |
| CN-113980581-B | Environment-friendly suspending agent based on sapphire grinding, and preparation method and application thereof | 浙江奥首材料科技有限公司 | 2022-06-14 | — | — | CN | disclosed |
| EP-3952991-A1 | RUSALATIDE ACETATE COMPOSITIONS | Affirmed Pharma, LLC (US) | 2022-02-16 | — | — | EP | disclosed |
| CN-113980581-A | Environment-friendly suspending agent based on sapphire grinding, and preparation method and application thereof | 浙江奥首材料科技有限公司 | 2022-01-28 | — | — | CN | disclosed |
| US-20200390869-A1 | RUSALATIDE ACETATE COMPOSITIONS | AFFIRMED PHARMA, LLC | 2020-12-17 | — | — | US | disclosed |
| WO-2020210087-A1 | RUSALATIDE ACETATE COMPOSITIONS | AFFIRMED PHARMA, LLC (US) | 2020-10-15 | — | — | WO | disclosed |
| WO-1998028336-A1 | POLYSACCHARIDE-PEPTIDE DERIVATIVES | MAP MEDICAL TECHNOLOGIES OY (FI) | 1998-07-02 | — | — | WO | disclosed |
| WO-1998013069-A2 | FLUORINATED COPOLYMERIC PHARMACEUTICAL ADJUNCTS | SUPRATEK PHARMA, INC. (CA) | 1998-04-02 | — | — | WO | disclosed |
| CN-1145094-A | Laundry detergent bar comprising fabric softening clay and cellulase | PROCTER & GAMBLE (US) | 1997-03-12 | — | — | CN | disclosed |
| EP-0566063-A1 | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1993-10-20 | — | — | EP | disclosed |
| US-4469615-A | Water treating compositions | KOHRYU INDUSTRIAL CO. LTD. (JP) | 1984-09-04 | — | — | US | disclosed |
| US-4381203-A | Coating solutions for zinc surfaces | AMCHEM PRODUCTS, INC. (US) | 1983-04-26 | — | — | US | disclosed |