Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.42 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HMGCR | P04035 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CPT2 | P23786 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL11359615 | 0.95 | KDM4E (0.46) | KDM4EGLRA1SLC6A9OR51E2ALDH1A1 | |
| Ethylenediamine SCHEMBL11272751 | 0.90 | KDM4E (0.43) | KDM4EGLRA1SLC6A9OR51E2ALDH1A1 | |
| SCHEMBL5320897 | 0.85 | KDM4E (0.48) | KDM4EGLRA1SLC6A9OR51E2ALDH1A1 | |
| SCHEMBL16374685 | 0.84 | ALDH1A1 (0.45) | KDM4EGLRA1SLC6A9OR51E2ALDH1A1 | |
| Adipic Acid SCHEMBL3977001 | 0.84 | NFKB1 (0.54) | KDM4EALDH1A1TSHRCYP2D6GABRR1 | |
| SCHEMBL4610249 | 0.83 | KDM4E (0.41) | KDM4EGLRA1SLC6A9OR51E2ALDH1A1 | |
| Adipic Acid SCHEMBL3419982 | 0.82 | LMNA (0.60) | KDM4EALDH1A1TSHRCYP2D6GABRR1 | |
| Hydrochloric Acid SCHEMBL27533813 | 0.81 | KDM4E (0.48) | KDM4EGLRA1SLC6A9OR51E2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL11274979 | 0.79 | KDM4E (0.35) | KDM4EACLY | |
| SCHEMBL18162193 | 0.79 | KDM4E (0.43) | KDM4EGLRA1SLC6A9OR51E2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0941120-A4 | BRANCHED PEPTIDE LINKERS | BRISTOL MYERS SQUIBB CO (US) | 2004-08-18 | — | — | EP | disclosed |
| EP-0941120-A1 | BRANCHED PEPTIDE LINKERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-09-15 | — | — | EP | disclosed |
| WO-1998019705-A1 | BRANCHED PEPTIDE LINKERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-05-14 | — | — | WO | disclosed |
| EP-0039226-B1 | RESIN COMPOSITION COMPRISING WATER-SOLUBLE POLYAMIDE AND VINYL ALCOHOL-BASED POLYMER | UNITIKA LTD. (JP) | 1985-10-02 | — | — | EP | disclosed |
| US-4073700-A | FROM GOLD CYANIDE IN THE PRESENCE OF A CHELATING AGENT | WEISBERG ALFRED M | 1978-02-14 | — | — | US | disclosed |